Table 3 Estimates of ORSCL, ORVF, ORMH, and ORG from simulated data with a binary exposure and a binary time-varying confounder (study period = M + 1 days). Results are shown graphically in Fig. 3b
M variables | ORSCL (95%CI) | ORVF (95%CI) | ORMH (95%CI) | ORG (2.5–97.5pct) | |
|---|---|---|---|---|---|
1 | exp(β) | 4.26 (2.72–6.66) | 4.27 (2.73–6.68) | 4.55 (2.37–8.73) | 4.26 (2.85–7.33) |
|  | exp(γ) | 1.68 (1.02–2.78) | 1.86 (1.11–3.11) |  | 1.68 (1.03–2.96) |
2 | exp(β) | 4.04 (2.85–5.75) | 4.04 (2.85–5.73) | 3.82 (2.49–5.86) | 4.04 (2.78–6.11) |
|  | exp(γ) | 1.84 (1.15–2.94) | 2.06 (1.28–3.30) |  | 1.84 (1.19–2.92) |
3 | exp(β) | 3.62 (2.60–5.04) | 4.11 (2.83–5.97) | 4.17 (2.71–6.43) | 4.10 (2.93–5.82) |
|  | exp(γ) | 2.12 (1.43–3.12) | 1.93 (1.31–2.86) |  | 2.21 (1.45–3.37) |
4 | exp(β) | 3.91 (2.86–5.34) | 4.19 (3.03–5.79) | 3.91 (2.66–5.75) | 4.09 (3.00–5.67) |
|  | exp(γ) | 2.14 (1.48–3.11) | 2.43 (1.66–3.54) |  | 2.20 (1.45–3.26) |
5 | exp(β) | 4.36 (3.18–5.97) | 4.07 (3.00–5.51) | 4.04 (2.78–5.86) | 4.02 (2.93–5.57) |
|  | exp(γ) | 1.86 (1.29–2.66) | 2.35 (1.62–3.41) |  | 1.92 (1.28–2.86) |
6 | exp(β) | 4.78 (3.51–6.52) | 3.98 (2.88–5.50) | 4.15 (2.93–5.88) | 4.12 (3.00–5.77) |
|  | exp(γ) | 1.92 (1.36–2.71) | 2.00 (1.37–2.92) |  | 1.87 (1.33–2.63) |
7 | exp(β) | 4.48 (3.26–6.15) | – | 4.42 (3.10–6.30) | 4.04 (2.94–5.59) |
|  | exp(γ) | 1.89 (1.34–2.67) | 2.03 (1.33–3.08) |  | 1.86 (1.30–2.70) |
8 | exp(β) | 4.90 (3.57–6.74) | 4.07 (2.50–6.63) | 3.88 (2.79–5.42) | 4.07 (2.93–5.68) |
|  | exp(γ) | 1.81 (1.29–2.53) | 1.76 (1.17–2.64) |  | 1.79 (1.24–2.51) |
9 | exp(β) | 5.24 (3.81–7.22) | 4.10 (2.76–6.08) | 4.47 (3.22–6.19) | 4.08 (2.96–5.65) |
|  | exp(γ) | 1.77 (1.27–2.48) | 2.10 (1.42–3.10) |  | 1.75 (1.23–2.48) |
10 | exp(β) | 5.08 (3.67–7.03) | – | 4.13 (2.99–5.70) | 4.06 (2.94–5.61) |
|  | exp(γ) | 1.77 (1.28–2.45) | 1.62 (1.08–2.42) |  | 1.76 (1.26–2.50) |
11 | exp(β) | 5.33 (3.85–7.38) | 4.07 (2.17–7.64) | 4.15 (3.01–5.72) | 4.07 (2.96–5.65) |
|  | exp(γ) | 1.78 (1.29–2.46) | 1.86 (1.26–2.76) |  | 1.73 (1.23–2.38) |
12 | exp(β) | 5.61 (4.06–7.75) | 4.12 (2.69–6.32) | 4.51 (3.29–6.18) | 4.07 (2.95–5.62) |
|  | exp(γ) | 1.92 (1.39–2.66) | 1.81 (1.24–2.64) |  | 1.86 (1.34–2.62) |
13 | exp(β) | 5.81 (4.19–8.04) | 4.06 (2.79–5.91) | 4.65 (3.40–6.36) | 4.02 (2.90–5.56) |
|  | exp(γ) | 1.93 (1.39–2.68) | 1.87 (1.28–2.73) |  | 1.88 (1.34–2.61) |
14 | exp(β) | 5.60 (4.02–7.79) | – | 4.05 (2.96–5.55) | 3.99 (2.87–5.53) |
|  | exp(γ) | 1.93 (1.40–2.66) | 2.10 (1.40–3.13) |  | 1.87 (1.35–2.57) |
15 | exp(β) | 5.83 (4.17–8.13) | 3.94 (2.42–6.42) | 3.85 (2.85–5.21) | 3.97 (2.86–5.50) |
|  | exp(γ) | 1.91 (1.38–2.63) | 2.04 (1.39–3.00) |  | 1.86 (1.35–2.57) |
16 | exp(β) | 6.05 (4.35–8.43) | 3.98 (2.68–5.92) | 3.88 (2.87–5.25) | 3.98 (2.88–5.52) |
|  | exp(γ) | 2.04 (1.47–2.82) | 2.11 (1.45–3.07) |  | 1.98 (1.41–2.72) |
17 | exp(β) | 5.94 (4.25–8.30) | – | 4.21 (3.09–5.73) | 3.97 (2.87–5.51) |
|  | exp(γ) | 2.06 (1.49–2.84) | 2.19 (1.48–3.23) |  | 2.02 (1.46–2.79) |
18 | exp(β) | 6.14 (4.39–8.59) | 4.08 (2.18–7.64) | 4.13 (3.05–5.59) | 3.99 (2.89–5.51) |
|  | exp(γ) | 2.02 (1.47–2.77) | 2.16 (1.48–3.15) |  | 1.95 (1.43–2.65) |
19 | exp(β) | 6.32 (4.52–8.85) | 4.00 (2.60–6.14) | 3.94 (2.94–5.29) | 3.98 (2.87–5.48) |
|  | exp(γ) | 2.07 (1.51–2.85) | 1.98 (1.37–2.88) |  | 2.01 (1.50–2.71) |
20 | exp(β) | 6.49 (4.64–9.08) | 3.94 (2.71–5.74) | 3.99 (2.98–5.34) | 3.98 (2.90–5.46) |
|  | exp(γ) | 2.16 (1.57–2.98) | 2.14 (1.47–3.11) |  | 2.05 (1.52–2.76) |
21 | exp(β) | 6.35 (4.52–8.91) | – | 4.16 (3.09–5.61) | 3.96 (2.88–5.46) |
|  | exp(γ) | 2.20 (1.60–3.01) | 2.20 (1.51–3.22) |  | 2.10 (1.53–2.81) |