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Table 5 Estimates of ORSCL and ORMH (95% CI), ORG (2.5–97.5pct): Japanese data on celecoxib-peripheral edema with study period = 84 days and Exposure Definition I

From: A novel weighting method to remove bias from within-subject exposure dependency in case-crossover studies

Study period

84 days

Days in 1 period

1 day

3 days

7 days

14 days

28 days

42 days

M

83

27

11

5

2

1

ORSCL

2.82 (2.14–3.71)

2.73 (2.08–3.60)

2.53 (1.93–3.33)

2.28 (1.74–2.99)

2.05 (1.54–2.74)

1.91 (1.38–2.64)

ORMH

1.99 (1.58–2.51)

1.98 (1.57–2.50)

1.97 (1.55–2.50)

1.94 (1.51–2.48)

1.93 (1.46–2.56)

1.91 (1.38–2.64)

ORG

1.99 (1.49–2.65)

1.98 (1.48–2.64)

1.97 (1.48–2.62)

1.94 (1.44–2.58)

1.93 (1.43–2.62)

1.91 (1.36–2.72)

  1. M is the number of control periods
  2. ORSCL: odds ratio by the standard conditional logistic regression; ORMH: odds ratio by the Mantel-Haenszel method; ORG: odds ratio by the Greenland’s method; 95%CI: 95% confidence interval; 2.5–97.5pct: 2.5 to 97.5 percentiles