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Table 2 Most common components of MACE (N = 58 studies)

From: Major adverse cardiovascular event definitions used in observational analysis of administrative databases: a systematic review

MACE Components

ICD-9

ICD-10

Both ICD-9/10

Individual components

 AMI (n = 45)

29

14

2

 Acute coronary syndrome / Ischemic Heart disease (n = 18)

12

5

1

 Stroke (n = 50)

30

17

3

 Heart failure (n = 15)

12

2

1

 All-cause death (n = 15)

10

5

0

 CV death (n = 9)

1

6

2

 Revascularization (n = 11)

7

4

0

 Other (n = 19)

15

3

1

Combinations

 Three-point MACE: AMI + Stroke+CV death (n = 5)

1

3

1

 Four-point MACE: AMI + Stroke+UA + CV death (n = 0)

0

0

0

 Five-point MACE: AMI + Stroke+UA + HF + CV death (n = 0)

0

0

0

 AMI + stroke+all-cause death (n = 8)

5

3

0

 AMI + stroke+HF + CV death (n = 0)

0

0

0

 AMI + stroke+HF + all-cause death (n = 2)

1

1

0

  1. Abbreviations: MACE Major adverse cardiovascular events, ICD International Classification of Diseases, AMI Acute myocardial infarction, CV Cardiovascular, UA Unstable angina, HF Heart failure