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Table 1 Frameworks for appraising applicability of studies

From: Appraising clinical applicability of studies: mapping and synthesis of current frameworks, and proposal of the FrACAS framework and VICORT checklist

Framework and/or First Author

Journal

Framework Focus

Year of Publication

AGREE I

Cluzeau et al. [29]

Quality and Safety in Health Care

Quality of CPG

2003

AGREE II

Brouwers et al. [30]

Canadian Medical Association J

 

2010

AGREE-REX

Brouwers et al. [31]

JAMA Network Open

Quality of CPG recommendations

2020

ASTAIRE

Cambon et al. [32]

BMC Public Health

Transferability of health promotion interventions

2013

EVAT

Khorsan et al. [33]

Evidence-Based Complementary and Alternative Medicine

Evidence for clinical decision-making

2014

GRADE

Guyatt et al. [11]

British Medical Journal

Quality of evidence and strength of recommendations

2008

GRADE EtD

 Clinical recommendations

Alonso-Coello et al. [18, 34]

British Medical Journal

Evidence usage in a structured and transparent way to inform and adapt clinical and public health decisions

2016

2016

 Coverage decisions

Parmelli et al. [35]

Int J of Tech Assessm in Health Care

2017

 Diagnostic/screening tests

Schünemann et al. [36]

Journal of Clinical Epidemiology

2017

 Health system and public health

Moberg et al. [37]

Health Research Policy and Systems

2018

 Multi-intervention comparisons

Piggott et al. [38]

Journal of Clinical Epidemiology

2021

GRASP

Khalifa et al. [39]

BMC Medical Informatics and Decision Making

Predictive tools for clinical decision support

2019

ISAT

Milat et al. [40]

Health Research Policy and Systems

Decision support tool for health policy makers and implementers

2020

PRECIS

Thorpe et al. [41]

Canadian Medical Association Journal

Pragmatic vs. exploratory trials for trial designers

2009

PR-Tool

Koppenaal et al. [42]

Journal of Clinical Epidemiology

Applicability of individual and SR of trials

2011

PROBAST

Moons et al. [43]

Annals of Internal Medicine

Risk of bias and applicability of prediction model studies

2019

RE-AIM

Glasgow et al. [22, 44]

American Journal of Public Health

Health Education Research

Evaluate and report on internal and external validity, and impact of health promotion programs

1999

2006

RoB 2

Sterne et al. [7]

British Medical Journal

Risk of bias in randomized trials

2019

RoBINS-I

Sterne et al. [6]

British Medical Journal

Risk of bias in non-randomised studies of interventions

2016

STP

Lavis et al. [45]

Health Research Policy and Systems

Applicability of the findings of a systematic review

2009

WHO-INTEGRATE EtD

Stratil et al. [46]

Cost Effectiveness and Resource Allocation

Decision criteria for health decision making

2020

Almeida et al. [47]

Int J of Tech Assessm in Health Care

Translation of HTA evidence into policy

2019

Atkins et al. [48]

Journal of Clinical Epidemiology

Applicability when comparing medical interventions for SR

2011

Berger et al. [49]

Value in Health

Relevance and credibility of observational studies for health care decision making

2014

Bonell et al. [50]

British Medical Journal

Generalizability in trials of health interventions

2006

Bornhoft et al. [51]

BMC Medical Research Methodology

Evaluation of clinical studies on external and model validity

2006

Burford et al. [52]

Journal of Clinical Epidemiology

Applicability of findings in systematic reviews of complex interventions for SR

2013

Green et al. [17]

Evaluation and the Health Professions

Relevance, generalizability, and applicability of research

2006

Gruen et al. [53]

Bulletin of the World Health Org

Generalizability of studies in LMIC for SR

2005

Linan et al. [54]

Journal of Evidence-Based Medicine

Clinical applicability of CPG

2020

Polus et al. [55]

Int J of Tech Assessm in Health Care

Applicability of a technology in the context of HTA

2017

  1. Notes. CPG clinical practice guidelines, HTA health technology assessment, LMIC low- and middle- income countries, SR systematic review