Table 3 Four true toxicity scenarios with the target DLT rates of 0.2 and 0.3 in boldface
From: An adaptive gBOIN design with shrinkage boundaries for phase I dose-finding trials
| Â | Target DLT rate =20% | Â | Target DLT rate =30% | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Scenario | 1 | 2 | 3 | 4 | 5 | Scenario | 1 | 2 | 3 | 4 | 5 |
1 | 0.01 | 0.10 | 0.20 | 0.30 | 0.35 | 3 | 0.01 | 0.20 | 0.30 | 0.40 | 0.50 |
2 | 0.01 | 0.18 | 0.20 | 0.30 | 0.35 | 4 | 0.01 | 0.25 | 0.30 | 0.40 | 0.50 |