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Table 1 Detailed description of case study variables used during simulation and their distribution within the Barwon Infant Study

From: Evaluation of multiple imputation approaches for handling missing covariate information in a case-cohort study with a binary outcome

Variable

Variable Type

Label

n (%)* (N = 1074)

n (%) missing

Outcome

 Food Allergy at 1 year (present)

Binary; Present/Absent

foodallergy

61 (7.8)

288 (26.8)

Exposure

 Vitamin D Insufficiency at Birth (present)

Binary; Present/Absent

vdi

149 (44.5)

739 (68.8)

Covariates

 Ethnicity (Caucasian)

Binary; Caucasian/Not Caucasian

cauc

772 (72.1)

3 (0.3)

 Maternal Vitamin D Supplements Usage (present)

Binary; Present/Absent

antevd

564 (78.8)

358 (33.3)

 Family History of Allergy (present)

Binary; Present/Absent

hxfamall

911 (86.1)

16 (1.5)

Number of Siblings

3-Level Categorical

nsib

 

0 (0.00)

 None

  

453 (42.2)

 

 One

  

383 (35.7)

 

 Two or more

  

238 (22.2)

 

Family Pet Ownership (present)

Binary; Present/Absent

petown

815 (80.5)

62 (5.8)

Formula Feeding at 6 months#

3-Level Categorical

formfeed6

 

189 (17.6)

 Exclusively Breast Fed

  

429 (46.6)

 

 Exclusively Formula Fed

  

320 (34.8)

 

 Mixed Feeding

  

171 (18.6)

 

Formula Feeding at 12 months#

3-Level Categorical

formfeed12

 

154 (14.3)

 Exclusively Breast Fed

  

271 (30.6)

 

 Exclusively Formula Fed

  

354 (40.0)

 

 Mixed Feeding

  

260 (29.4)

 

Auxiliary

Maternal Age at Birth

 

mage

32.1 (4.78)

3 (0.3)

Family SEIFA Classification

3-Level Categorical

seifa

 

20 (1.9)

Low

  

268 (25.4)

 

Middle

  

204 (19.4)

 

High

  

582 (55.2)

 
  1. *Mean and standard deviation given for maternal age; percentage given is exclusive of missing data
  2. #Formula feeding variables were not included in the simulation study
  3. SEIFA Socioeconomic index for area