From: Registration and primary outcome reporting in behavioral health trials
Studies | n (%) |
---|---|
Concordant vs. discordant studies ( n =53) | |
Concordant | 16 (30) |
Discordant | 37 (70) |
Discrepancies identified in discordant studies ( n =37) | |
Primary outcome(s) described in registration was/were not explicitly defined | 19 (36) |
Registration did not state how primary outcome(s) would be measured/codified | 16 (30) |
Published manuscript(s) reporting results of registered trial include at least one unregistered primary outcome | 16 (30) |
Primary outcome(s) described in registration was/were not measured according to registration prescribed timing protocol | 14 (26) |
Published manuscript(s) reporting results of registered trial did not report on all registered primary outcomes | 11 (21) |
Secondary outcome(s) described in registration was/were promoted to primary outcome(s) in published manuscript(s) reporting trial results | 5 (9) |
Registration prescribed timing protocol for measuring primary outcome(s) was not adequately defined | 4 (7) |
Primary outcome(s) described in registration was/were de-emphasized or demoted to secondary outcome(s) in published manuscript(s) reporting trial results | 4 (7) |