Development | External validation: COVID-19 | External validation: influenza | ||||||||||||
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ClinFormatics | CUIMC | HIRA | SIDIAP | TRDW | VA | AUSOM | AU-ePBRN | CCAE | IPCI | JMDC | MDCD | MDCR | Optum EHR | |
Number of participants | 2,082,277 | 2,731 | 1,985 | 37,950 | 395 | 1,446 | 3,105 | 2,791 | 3,146,801 | 29,132 | 1,276,478 | 536,806 | 248,989 | 1,654,157 |
Hospitalization with pneumonia (Outcome proportion %) | 105,030 (5.04) | N/A | 89 (4.48) | 1,223 (1.11) | 21 (5.32) | 149 (10.30) | 49 (1.58) | 29 (1.04) | 33,824 (1.07) | 22 (0.08) | 728 (0.06) | 32,987 (6.15) | 31,059 (12.47) | 34,229 (2.07) |
Hospitalization with pneumonia requiring intensive services or death (Outcome proportion %) | 29,905 (1.44) | 134 (4.91) | 22 (1.11) | N/A | 5 (1.27) | 38 (2.63) | 5 (0.16) | 3 (0.11) | 4,856 (0.02) | 24 (0.08) | 65 (0.01) | 7,226 (1.35) | 3,628 (1.46) | 7,368 (0.45) |
Death (Outcome proportion %) | 11,407 (0.55) | 335 (12.27) | 43 (2.17) | 406 (1.07) | 1 (0.25) | 43 (2.97) | 5 (0.16) | 4 (0.14) | 965 (0.03) | 24 (0.08) | 75 (0.01) | 2,603 (0.48) | 1,354 (0.54) | 3,513 (0.21) |
Age (% above 65) | 26.1 | 38.9 | 15.6 | 17.9 | 18.2 | 37.3 | 11.9 | 23.1 | 12.5 | 16.9 | 16.0 | 14.2 | 96.2 | 30.0 |
Sex (%, male) | 44.4 | 47.2 | 43.5 | 43.4 | 49.6 | 81.4 | 41.7 | 44.5 | 42.7 | 43.7 | 56.8 | 29.2 | 45.9 | 40.1 |
Cancer (%) | 12.6 | 17.1 | 9.8 | 6.3 | 11.6 | 17.0 | 7.7 | 8.2 | 6.2 | 3.7 | 2.5 | 8.9 | 35.2 | 10.6 |
COPD (%) | 10.2 | 9.3 | 4.9 | 2.5 | 6.3 | 20.5 | 2.7 | 3.1 | 2.7 | 2.7 | 0.5 | 19.8 | 26.6 | 7.6 |
Diabetes (%) | 20.5 | 30.9 | 23.1 | 8.0 | 19.7 | 35.2 | 3.8 | 13.0 | 11.4 | 6.7 | 8.3 | 27.4 | 36.1 | 15.3 |
Heart disease (%) | 31.0 | 40.1 | 17.1 | 11.2 | 25.8 | 44.7 | 7.7 | 12.9 | 16.5 | 7.5 | 8.0 | 36.1 | 68.2 | 23.4 |
Hypertension (%) | 44.2 | 51.6 | 26.3 | 14.8 | 38.5 | 63.0 | 13.9 | 27.0 | 29.1 | 12.4 | 11.4 | 49.8 | 80.4 | 36.1 |
Hyperlipidemia (%) | 46.8 | 40.6 | 39.9 | 11.4 | 32.9 | 62.5 | 3.3 | 20.2 | 21.8 | 4.6 | 15.2 | 36.0 | 69.6 | 34.2 |
Kidney disease (%) | 18.7 | 31.2 | 17.0 | 11.0 | 24.3 | 32.4 | 7.6 | 6.2 | 9.0 | 1.2 | 5.1 | 23.4 | 35.5 | 14.9 |