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Table 4 Application results

From: Weighted composite time to event endpoints with recurrent events: comparison of three analytical approaches

Weighting scheme p-value Estimator
  Wei-Lachin Rauch Bakal Wei-Lachin Rauch
Weight for death: 1 0.34 0.10 0.40 1.05 1.38
Weight for readmission: 1      
Weight for death: 1 0.29 0.09 0.39 1.07 1.39
Weight for readmission: 0.9      
Weight for death: 1 0.21 0.07 0.37 1.11 1.40
Weight for readmission: 0.7      
Weight for death: 1 0.14 0.05 0.32 1.17 1.42
Weight for readmission: 0.5      
Weight for death: 1 0.09 0.04 0.23 1.25 1.43
Weight for readmission: 0.3      
Weight for death: 1 0.05 0.03 0.05 1.36 1.44
Weight for readmission: 0.1      
  1. one-sided test in favour of no chemotherapy; estimated weighted composite effect at end of study period for chemotherapy vs. no chemotherapy; composite endpoint = (recurrent) hospitalization plus death