Table 5 Proportions of decisions at the end of the trial in seven scenarios when K=3
Subset A | Subset B | Subset C | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Scenarios | Pattern | Go with EP ∗ | Go with SP (efficacy/ interaction) ∗ | nA | Go with SP (efficacy/ interaction) ∗ | nB | Go with SP (efficacy/ interaction) ∗ | nC | Go with A and B | Go with A and C | Go with B and C |
Scenario 1 | 1 | 0.94 | 0.02 | 266.55 | 0.02 | 266.43 | 0.02 | 267.02 | 0.00 | 0.00 | 0.00 |
2 | 0.90 | 0.02 | 137.03 | 0.04 | 268.99 | 0.04 | 393.98 | 0.00 | 0.00 | 0.00 | |
3 | 0.87 | 0.05 | 474.35 | 0.06 | 272.87 | 0.02 | 52.78 | 0.00 | 0.00 | 0.00 | |
4 | 0.89 | 0.04 | 268.64 | 0.04 | 394.67 | 0.02 | 136.68 | 0.00 | 0.00 | 0.00 | |
5 | 0.86 | 0.06 | 273.72 | 0.02 | 53.72 | 0.05 | 472.56 | 0.00 | 0.00 | 0.00 | |
Scenario 2 | 1 | 0.87 | 0.04 | 265.96 | 0.04 | 265.86 | 0.04 | 268.18 | 0.00 | 0.00 | 0.00 |
2 | 0.71 | 0.02 | 121.46 | 0.10 | 269.10 | 0.16 | 409.45 | 0.00 | 0.00 | 0.01 | |
3 | 0.44 | 0.31 | 480.78 | 0.21 | 279.86 | 0.02 | 39.36 | 0.02 | 0.00 | 0.00 | |
4 | 0.71 | 0.09 | 268.44 | 0.16 | 408.75 | 0.03 | 122.81 | 0.01 | 0.00 | 0.00 | |
5 | 0.46 | 0.21 | 282.57 | 0.01 | 39.47 | 0.30 | 477.95 | 0.00 | 0.01 | 0.00 | |
Scenario 3 | 1 | 0.56 | 0.00 | 182.53 | 0.00 | 182.83 | 0.44 | 434.64 | 0.00 | 0.00 | 0.00 |
2 | 0.09 | 0.00 | 48.59 | 0.00 | 98.19 | 0.90 | 653.22 | 0.00 | 0.00 | 0.00 | |
3 | 0.82 | 0.03 | 444.14 | 0.03 | 247.72 | 0.13 | 108.13 | 0.00 | 0.00 | 0.00 | |
4 | 0.73 | 0.01 | 218.48 | 0.01 | 328.03 | 0.26 | 253.49 | 0.00 | 0.00 | 0.00 | |
5 | 0.01 | 0.00 | 78.30 | 0.00 | 13.36 | 0.98 | 708.34 | 0.00 | 0.00 | 0.00 | |
Scenario 4 | 1 | 0.76 | 0.00 | 222.18 | 0.10 | 289.78 | 0.09 | 288.05 | 0.00 | 0.00 | 0.04 |
2 | 0.33 | 0.00 | 75.06 | 0.17 | 276.00 | 0.32 | 448.94 | 0.00 | 0.00 | 0.16 | |
3 | 0.46 | 0.02 | 342.21 | 0.50 | 417.39 | 0.02 | 40.39 | 0.00 | 0.00 | 0.00 | |
4 | 0.57 | 0.01 | 192.46 | 0.34 | 485.06 | 0.04 | 122.48 | 0.00 | 0.00 | 0.03 | |
5 | 0.21 | 0.02 | 145.08 | 0.02 | 34.79 | 0.73 | 620.14 | 0.00 | 0.00 | 0.01 | |
Scenario 5 | 1 | 0.68 | 0.00 | 204.21 | 0.02 | 244.22 | 0.21 | 351.56 | 0.00 | 0.00 | 0.09 |
2 | 0.14 | 0.00 | 52.01 | 0.02 | 183.50 | 0.54 | 564.49 | 0.00 | 0.00 | 0.28 | |
3 | 0.63 | 0.02 | 379.82 | 0.30 | 364.59 | 0.04 | 55.59 | 0.00 | 0.00 | 0.01 | |
4 | 0.68 | 0.00 | 206.75 | 0.13 | 426.00 | 0.09 | 167.25 | 0.00 | 0.00 | 0.08 | |
5 | 0.06 | 0.00 | 87.94 | 0.00 | 17.59 | 0.91 | 694.47 | 0.00 | 0.00 | 0.02 | |
Scenario 6 | 1 | 0.67 | 0.01 | 216.19 | 0.31 | 377.23 | 0.00 | 206.58 | 0.00 | 0.00 | 0.00 |
2 | 0.59 | 0.02 | 106.91 | 0.39 | 402.04 | 0.00 | 291.05 | 0.00 | 0.00 | 0.00 | |
3 | 0.22 | 0.03 | 296.85 | 0.75 | 476.13 | 0.00 | 27.02 | 0.00 | 0.00 | 0.00 | |
4 | 0.23 | 0.02 | 156.39 | 0.74 | 572.35 | 0.00 | 71.26 | 0.00 | 0.00 | 0.00 | |
5 | 0.84 | 0.05 | 263.31 | 0.11 | 98.39 | 0.00 | 438.31 | 0.00 | 0.00 | 0.00 | |
Scenario 7 | 1 | 0.40 | 0.00 | 157.15 | 0.59 | 490.36 | 0.00 | 152.49 | 0.00 | 0.00 | 0.00 |
2 | 0.30 | 0.00 | 70.66 | 0.70 | 527.77 | 0.00 | 201.56 | 0.00 | 0.00 | 0.00 | |
3 | 0.06 | 0.01 | 182.16 | 0.93 | 601.83 | 0.00 | 16.00 | 0.00 | 0.00 | 0.00 | |
4 | 0.03 | 0.00 | 87.41 | 0.96 | 671.51 | 0.00 | 41.08 | 0.00 | 0.00 | 0.00 | |
5 | 0.76 | 0.03 | 241.06 | 0.21 | 147.67 | 0.00 | 411.27 | 0.00 | 0.00 | 0.00 | |