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Fig. 15 | BMC Medical Research Methodology

Fig. 15

From: Analysis approaches to address treatment nonadherence in pragmatic trials with point-treatment settings: a simulation study

Fig. 15

Mean risk difference (RD) versus the nonadherence rate for DAG 2. The grey lines are the lower and upper bound of the NPCB method. The ITT and baseline-adjusted ITT superimposed on each other. Abbreviations: RD: risk difference, ITT: intention-to-treat, PP: per-protocol, AT: as-treated, IP-weighted PP: inverse probability-weighted per-protocol, 2SLS: two-stage least square, 2SRI: two-stage residual inclusion, NPCB: nonparametric causal bound

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BMC Medical Research Methodology

ISSN: 1471-2288

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