Skip to main content
Fig. 5 | BMC Medical Research Methodology

Fig. 5

From: Analysis approaches to address treatment nonadherence in pragmatic trials with point-treatment settings: a simulation study

Fig. 5

Bias versus the nonadherence rate for the null and non-null effect for simulation setting 3. The 2SLS and 2SRI methods share the same line, and the baseline-adjusted PP and IP-weighted PP share the same line. The bias is out of the bound [-0.6,0.6] for the 2SLS and 2SRI methods for severe violation of the exclusion restriction. Abbreviations: PP: per-protocol, IP-weighted PP: inverse probability-weighted per-protocol, 2SLS: two-stage least square, 2SRI: two-stage residual inclusion

Back to article page

BMC Medical Research Methodology

ISSN: 1471-2288

Contact us