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Fig. 3 | BMC Medical Research Methodology

Fig. 3

From: The impact of moderator by confounder interactions in the assessment of treatment effect modification: a simulation study

Fig. 3

Estimated subgroup-specific treatment effects and effect modification where the moderator has a prevalence of 0.1. \({\widehat{\beta }}_{T|M=m}\) is the subgroup-specific treatment effect and \({\widehat{\beta }}_{TM}\) is the treatment effect moderator effect. (a) adjusting for no moderator-confounders interactions, (b) adjusting for the one moderator-confounder interaction, (c) adjusting for all possible moderator-confounder interactions, (d) subgroup-specific confounding adjustment. (1) Regression adjustment, (2) Propensity score covariate adjustment, (3) IPTW, (4) Propensity score matching

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