BMC Medical Research Methodology

Table 1 Parameter estimates under left-censored reduced and extended BCT and normal models

From: Distributional regression in clinical trials: treatment effects on parameters other than the mean

		Reduced model						Extended model
		BCT			NO			BCT			NO
Parameter	Coefficient	Estimate	SE	p	Estimate	SE	p	Estimate	SE	p	Estimate	SE	p
μ	(Intercept)	−0.129	0.007	< 0.001	0.668	0.005	< 0.001	− 0.088	0.006	< 0.001	0.745	0.008	< 0.001
μ	baseline	0.813	0.009	< 0.001	0.236	0.004	< 0.001	0.879	0.008	< 0.001	0.319	0.008	< 0.001
μ	sex										−0.017	0.006	0.003
μ	treatment	−0.014	0.005	0.004	−0.005	0.004	0.224	−0.018	0.005	< 0.001	−0.005	0.004	0.166
σ	(Intercept)	−1.959	0.019	< 0.001	− 1.818	0.009	< 0.001	−2.796	0.050	< 0.001	−1.890	0.025	< 0.001
σ	baseline							−1.426	0.039	< 0.001	−0.230	0.017	< 0.001
σ	sex							−0.158	0.037	< 0.001	−0.154	0.024	< 0.001
σ	treatment							0.073	0.030	0.014
ν	(Intercept)	0.426	0.069	< 0.001				1.109	0.105	< 0.001
ν	baseline							0.153	0.045	0.001
ν	treatment							0.124	0.076	0.101
τ	(Intercept)	0.287	0.007	< 0.001				−0.029	0.006	< 0.001
τ	baseline							−1.184	0.008	< 0.001

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ISSN: 1471-2288

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