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Table 3 Parameter estimates under reduced and extended JSU and normal models

From: Distributional regression in clinical trials: treatment effects on parameters other than the mean

 

Reduced model

Extended model

JSU

NO

JSU

NO

Parameter

Coefficient

Estimate

SE

p

Estimate

SE

p

Estimate

SE

p

Estimate

SE

p

μ

(Intercept)

82.142

2.456

< 0.001

80.322

2.550

< 0.001

79.722

2.576

< 0.001

79.889

2.560

< 0.001

μ

baseline

−0.609

0.018

< 0.001

−0.594

0.019

< 0.001

− 0.589

0.019

< 0.001

− 0.590

0.019

< 0.001

μ

treatment

0.514

0.676

0.447

0.101

0.706

0.886

0.042

0.694

0.952

0.041

0.704

0.954

σ

(Intercept)

2.867

0.017

< 0.001

2.868

0.014

< 0.001

2.473

0.125

< 0.001

2.519

0.100

< 0.001

σ

baseline

 

0.003

0.001

< 0.001

0.003

0.001

< 0.001

σ

treatment

−0.067

0.031

0.030

−0.073

0.028

0.011

ν

(Intercept)

1.259

0.353

< 0.001

 

4.018

2.178

0.065

 

ν

baseline

   

−0.018

0.014

0.195

τ

(Intercept)

1.057

2.456

< 0.001

1.160

2.576

< 0.001