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Fig. 9 | BMC Medical Research Methodology

Fig. 9

From: Using linear and natural cubic splines, SITAR, and latent trajectory models to characterise nonlinear longitudinal growth trajectories in cohort studies

Fig. 9

Effect of increasing the number of knots in the random effects spline on the individual growth velocity curves from the natural cubic spline LME model. Figure shows velocity curves for 5 randomly selected individuals, obtained from natural cubic spline LME models in PBMAS males with 2, 4, and 6 knots for the random effects spline curve. All models included 6 knots in the fixed effects spline curve. All knots were placed at quantiles of age distribution

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