|
IQ1
|
What are the main symptoms of children infected with the novel coronavirus?
|
6.33
|
Yes. According to experts’ comments, we revised the wording of this clinical question
|
Clinical question 1: What are the symptoms of children with COVID-19 and who needs further assessment?
|
|
IQ2
|
What is confirmatory test for diagnosis novel coronavirus infection in children?
|
6.19
|
Yes. According to experts’ comments, we combined IQ2 and IQ8 into one question
|
Clinical question 3: Should computed tomography (CT) scan be used for the diagnosis and monitoring of children with COVID-19?
|
|
IQ3
|
How to conduct screening to novel coronavirus for suspected childhood infection in hospitals?
|
6.17
|
No. According to experts’ comments, this clinical question was not a priority in this phase
|
NA
|
|
IQ4
|
How to hierarchically manage children with novel coronavirus infection (including asymptomatic infected children)?
|
5.96
|
Yes. According to experts’ comments, the clinical question is answered in the form of a treatment pathway diagram
|
For the pathway diagram, please refer to the original maintext of the rapid advice guidelines for management of children with COVID-19 [10]
|
|
IQ5
|
How to effectively prevent children getting infected novel coronavirus? (Tips for protecting children from novel coronavirus infection)?
|
5.96
|
No. According to experts’ comments, this clinical question not belong to our guideline scope
|
NA
|
|
IQ6
|
Should new antiviral medications (such as lopinavir/ritonavir, remdesivir (GS-5734)) be used to treat in children with novel coronavirus infection?
|
5.85
|
Yes. According to experts’ comments, we combined IQ6 and IQ9 into one question and revised the wording
|
Clinical question 4: Should antiviral drugs such as ribavirin, interferon, remdesivir (GS-5734), lopinavir/ritonavir or oseltamivir be used to treat children with COVID-19?
|
|
IQ7
|
Should systemic corticosteroid be used to treat children with novel coronavirus infection?
|
5.83
|
Yes. According to experts’ comments, we revised the wording of this clinical question
|
Clinical question 6: Should systemic corticosteroids be used to treat children with severe COVID-19?
|
|
IQ8
|
Do children with non-severe novel coronavirus infection need imaging tests?
|
5.69
|
Yes. According to experts’ comments, we combined IQ2 and IQ8 into one question
|
Clinical question 3: Should computed tomography (CT) scan be used for the diagnosis and monitoring of children with COVID-19?
|
|
IQ9
|
Should traditional antiviral medications (such as ribavirin, interferon) be used to children with novel coronavirus infection?
|
5.63
|
Yes. According to experts’ comments, we combined IQ6 and IQ9 into one question
|
Clinical question 4: Should antiviral drugs such as ribavirin, interferon, remdesivir (GS-5734), lopinavir/ritonavir or oseltamivir be used to treat children with COVID-19?
|
|
IQ10
|
Where could parents and their children get reliable and evidence-based information about novel coronavirus epidemic and prevention?
|
5.63
|
Yes. According to experts’ comments, we revised the wording of this clinical question
|
Clinical question 10: How should parents be advised to get information on SARS-CoV-2 infection?
|
|
IQ11
|
How to manage a child who has history of epidemiological exposure but without symptoms?
|
5.57
|
Yes. According to experts’ comments, we combined IQ6 and IQ9 into one question
|
Clinical question 2: How should children who have had contact with COVID-19 patients be managed?
|
|
IQ12
|
Should IVIG be used to treat children with severe novel coronavirus severe infection?
|
5.56
|
Yes. According to experts’ comments, we revised the wording of this clinical question
|
Clinical question 7: Should intravenous immunoglobulin (IVIG) be used to treat children with severe COVID-19?
|
|
IQ13
|
For children with no history of epidemiological exposure, what are the indications or symptoms for screening novel coronavirus?
|
5.37
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ14
|
Should CT test be better than normal chest X-ray in children with severe novel coronavirus pneumonia?
|
5.35
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ15
|
What are the imaging features of children with novel coronavirus infection in lungs, are they specific?
|
5.35
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ16
|
How long is the average incubation period for children infected with novel coronavirus?
|
5.31
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ17
|
What is the severity for novel coronavirus infection in children compared to adults?
|
5.15
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ18
|
What is the prognosis of children with novel coronavirus infection?
|
5.12
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ19
|
How to conduct psychological assessment and therapy for children diagnosed with novel coronavirus infection?
|
4.96
|
Yes. We reached consensus that this clinical question was a priority issue for this guideline
|
Clinical question 8: What is appropriate supportive care for children with severe COVID-19?
|
|
IQ20
|
Could the novel coronavirus be vertically transmitted (mother to infant, breastfeeding)? If so, is there any difference in risk between natural delivery and caesarean section?
|
4.94
|
Yes. We reached consensus that this clinical question was a priority issue for this guideline
|
Clinical question 9: Should mothers with COVID-19 continue to breastfeed their babies?
|
|
IQ21
|
Should antibiotic agents be used to treat novel coronavirus infection?
|
4.91
|
Yes. According to experts’ comments, this clinical question was a priority issue for this guideline
|
Clinical question 5: Should antibiotics be used to treat children with COVID-19?
|
|
IQ22
|
What are the predisposing factors (gender, age, underlying diseases, ethnic differences) for novel coronavirus infection in children?
|
4.85
|
No. According to experts’ comments, this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ23
|
Does the complete blood count (CBC) test for children with early 2019-nCoV infection have a predictive effect on the severity of the disease?
|
4.85
|
No. According to experts’ comments, this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ24
|
Could a multidisciplinary cooperation improve the outcomes for children with severe novel coronavirus infection?
|
4.62
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ25
|
How susceptible are children compared to adults for novel coronavirus?
|
4.33
|
No. We reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
|
IQ26
|
What is the severity for 2019-nCoV infection in children (e.g., mortality and ICU admission rates) compared to SARS/MERS?
|
4.28
|
No. We members reached consensus that this clinical question was not a priority issue for this guideline
|
NA
|
