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Table 2 True prevalence results (mean and quantile of the 95% credible interval (Q) of the toy example with 24% and 5% apparent prevalence, 500 sample size, 120/25 positive tests with consistent assumptions on sensitivity (80%) and specificity (90%). Speybroek et al. 2012 Model 1 assumes fixed values for Se and Sp, while Model 2 assumes Se∼Unif(0.7,0.9) and Sp∼Unif(0.85,0.95). For the |tPRiors| example, Se∼Beta(195.76,48.94) and Sp∼Beta(135.86,15.1), while for Setup A: πt∼Beta(1,1) and Setup B: πt∼Beta(1.3,1.3)

From: |tPRiors |: a tool for prior elicitation and obtaining posterior distributions of true disease prevalence

 

Speybroek et al. 2012

tPRiors

 

Model 1

Model 2

Setup A.

Setup B.

Measure

24%

5%

24%

5%

24%

5%

24%

5%

Mean

0.2015

0.0048

0.2008

0.0096

0.2004

0.0103

0.2026

0.0127

2.5% Q

0.1493

0.0001

0.1133

0.0003

0.1266

0.0003

0.1203

0.0008

97.5% Q

0.2577

0.0173

0.2927

0.0336

0.2705

0.0327

0.2764

0.0367