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Table 3 Data Description

From: Applications of Bayesian shrinkage prior models in clinical research with categorical responses

Data

Availability

N, P

Variables

Outcome

Pima Indians Diabetes

R package “mlbench” [40]

768,8

no. of times pregnant (x1), glucose (x2), pressure (x3), triceps: Triceps skin fold thickness (mm) (x4), insulin (x5), BMI (x6), pedigree (x7), Age (x8)

tested positive for diabetes (y=1), negative (y=0)

Colon

R package ‘HiDimDA’ [41]

62, 2000

human genes

40 tumor (y=1) & 22 normal (y=0) colon tissues

ADNI

Alzheimer’s Disease Neu-roimaging Initiative (ADNI) database (adni.loni.usc.edu) R package ADNIMERGE [42]

14712, 113, after pre-processing: 911, 22

Age, CDRSB_bl: Clinical Dementia Rating Sum of Boxes (core), ADAS11_bl: 11 item-AD Cognitive Scale (score), ADAS13_bl: 13 item-AD Cognitive Scale (score), MMSE_bl: Mini-Mental State Examination (score), RAVLT_immediate_bl, RAVLT_learning_bl, RAVLT_forgetting_bl, RAVLT_perc_forgetting_bl: Rey’s Auditory Verbal Learning Test (scores for immediate response, learning, forgetting and percentage forgetting), FAQ_bl: Functional Activities Questionnaire, APOE4: APOE4 gene presence, Hippocampus_bl: Volume of hippocampus, Ventricles_bl: Volume of ventricles, WholeBrain_bl: volume of Brain, Fusiform_bl: The volume of the fusiform gyrus, Entorhinal_bl: The volume of the entorhinal cortex, MidTemp_bl: The volume of the middle temporal gyrus, ICV: Intra Cranial Volume, PTGENDER: Participant’s gender, PTETHCAT: Participant’s ethnicity, PTRACCAT: Participant’s race, PTMARRY: Participant’s marital status

LR model: AD (y=1), EMCI or LMCI (y=0); MLR model: AD (y=2), EMCI (y=1), LMCI (y=0)

OASIS

Open Access Series of Imaging Studies (OASIS) [43]

373, 15; after pre-processing 373, 8

Visit: number of visits, gender, age, EDUC: Education, SES: Socioeconomic status as assessed by the Hollings head Index of Social Position, MMSE: Mini-Mental State Examination score, nWBV: Normalized whole brain volume, ASF: Atlas Scaling Factor

CDR: Clinical Dementia Rating (0 = no dementia, 0.5 = very mild AD, 1 = mild AD, 2 = moderate AD); For LR model: mild AD or AD (y=1), no dementia or very mild AD (y=0); For MLR model: mild AD or AD (y=2), no dementia (y=0), very mild AD (y=1)