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Table 2 Bayesian fixed/adaptive designs investigated

From: Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs

 

Early success

Early futility

Late success

Late futility

Bayesian Fixed Design

-

-

-

-

Bayesian Adaptive Design 1

Skeptical prior

-

Skeptical prior

Skeptical prior

Bayesian Adaptive Design 2

-

Enthusiastic prior

Enthusiastic prior

Enthusiastic prior

Bayesian Adaptive Design 3

Skeptical prior

Enthusiastic prior

Skeptical prior

Enthusiastic prior

Bayesian Adaptive Design 4

Non-informative prior

Non-informative prior

Non-informative prior

Non-informative prior