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Table 3 Virtual Subject Response Scenarios

From: Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs

Scenario

Ctrl

Mean (SD)

Trt

Mean (SD)

Difference between Trt. and Ctrl

Mean (SD)

Trt. 0

(H0, no difference)

0 (0.07)

0 (0.07)

0 (0.10)

Trt. 0.02

(Small difference)

0 (0.07)

0.02 (0.07)

0.02 (0.10)

Trt. 0.05

(H1, target difference)

0 (0.07)

0.05 (0.07)

0.05 (0.10)

Trt. 0.08

(Large difference)

0 (0.07)

0.08 (0.07)

0.08 (0.10)

Trt. -0.05

(Harmful scenario)

0 (0.07)

-0.05 (0.07)

-0.05 (0.10)

  1. Trt treatment, Ctrl control, SD standard deviation