More than one third of clinical practice guidelines on low back pain overlap in AGREE II appraisals. Research wasted?

Table 4 Domain score variability of overlapping CPGs assessed by at least three appraisals

CPG	D1 (IQR)	D2 (IQR)	D3 (IQR)	D4 (IQR)	D5 (IQR)	D6 (IQR)	Mean
ICSI 2018 [44]	8	5.8	12.2	5.1	18	16.8	11
ACP 2017 [47]	7	29	6.4	11.1	11.9	23	14.7
CCGI 2018 [60]	3.7	26.7	1	21.3	30	17	16.6
CAAM 2016 [42]	5.5	8.8	14.9	50	6.3	20.8	17.7
SIGN 2013 [62]	15	11.1	19	20	18	27	18.4
DHA 2017 [45]	8	32	13	8	29	24	19
NICE 2016 [63]	9.9	22.1	9.6	8.6	30.9	34.7	19.3
APS 2009 [65]	14.9	19.7	18.8	8.6	34.5	23.7	20
OMG 2012 [61]	5.7	17.1	20.3	66.9	21	12.3	23.9
APTA 2012 [56]	20.5	12.7	23.9	24.3	33.7	36.8	25.3
VaDod 2017 [48]	12.7	19.7	25.8	12.1	29.5	52.1	25.3
ICSI 2012 [54]	22	37.3	33	16.9	14	33	26
KCE 2017 [43]	8	30.7	19.4	16.6	48	37.6	26.7
Cheng 2012 [59]	53.4	35	17.8	44.3	12.2	0	27.1
CCGPP 2016 [55]	27	44.2	16.9	25.4	15.8	37.1	27.7
NASS 2014 [51]	14	25	21.8	49	6.7	70.3	31.1
KNGF 2013 [46]	28.5	7.2	56.1	27	37.9	37.5	32.4
NICE 2009 [64]	8.3	22.2	37.5	11.1	47.9	70.8	33
ASIPP 2013 [49]	18.1	21	21.3	32.9	33.9	78.1	34.2
NASS 2013 [50]	13	45	35	50	56	54	42.2
PSP 2017 [52]	52.8	53	12.4	63.6	42	41.7	44.2
DAI 2017 [58]	71	56	43	33	36	41.7	46.8
TOP 2017 [53]	24.6	56	66	14.2	50.9	97	51.4
Mean	19.6	27.7	23.7	27	28.9	38.6	-

Variability is expressed as the IQR (quartile 3-quartile 1) of domain scores for overlapping CPGs. D, domain. Domain 1: Scope and Purpose, Domain 2: Stakeholder involvement, Domain 3: Rigour of Development, Domain 4: Clarity of presentation, Domain 5: Applicability, Domain 6: Editorial Independence
ACP American College of Physicians, APS American Pain Society, APTA American Physical Therapy Association, ASIPP American Society of Interventional Pain Physicians, CAAM China Association of Acupuncture-Moxibustion, CCGI Canadian Chiropractic Guideline Initiative, CCGPP Council on Chiropractic Guidelines and Practice Parameters, DAI Deutsches Ärzteblatt International, DHA Danish Health Authority, ICSI Institute for Clinical Systems Improvement, KCE Belgian Health Care Knowledge Centre, KNGF Koninklijk Nederlands Genootschap voor Fysiotherapie, NASS North American Spine Society, NICE National Institute for Health and Care Excellence, OMG Ottawa Methods Group, PSP Polish Society of Physiotherapy, SIGN Scottish Intercollegiate Guidelines Network, TOP Toward Optimized Practice Low Back Pain Working Group, VADoD Veterans Affairs/Department of Defense Collaboration Office

ISSN: 1471-2288