Skip to main content

Table 8 Estimates of regression parameters and their standard error obtained from MLE and Firth’s procedure by fitting Weibull AFT model for time-to-event data with outcome both respiratory disease and pulmonary embolus

From: On estimation for accelerated failure time models with small or rare event survival data

 

Respiratory disease

Pulmonary embolus

 

MLE

Firth

MLE

Firth

Predictors

Estimates

SE

Estimates

SE

Estimates

SE

Estimates

SE

Treatment

0.204

0.478

0.124

0.284

-0.588

1.086

-0.292

0.575

Age

-1.131

0.419

-0.755

0.243

-1.481

0.900

-0.913

0.471

WT

-0.535

0.351

-0.307

0.202

0.218

0.821

0.070

0.445

PF

14.193

-0.259

0.750

26.677

-0.676

1.518

HX

0.001

0.488

− 0.037

0.289

-0.646

1.121

− 0.463

0.625

HG

14.733

6,113.595

0.857

0.751

− 0.672

1.284

− 0.585

0.672

SZ

14.605

− 0.309

0.731

− 3.777

1.697

− 2.472

0.895

SG

0.083

0.463

0.025

0.076

-0.503

1.077

− 0.029

0.146

Intercept

6.772

0.904

5.931

0.336

10.031

2.075

8.942

0.969

scale (b)

0.779

0.262

0.646

0.073

1.657

3.438

1.423

0.159

  1. AG = age, WT = weight index, PF= performance rating, HX= history of cardiovascular disease, HG= serum haemoglobin, SZ= size of primary lesion, SG= Gleason stage/grade category