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Table 2 Imbalances in baseline computed tomography results

From: Risk of selection bias assessment in the NINDS rt-PA stroke study

Center ID

Time Stratum

Baseline Differences (% Placebo vs. % Alteplase) or (Placebo Mean vs. Alteplase Mean)

Allocation Difference (Δ)

3

0-90 Min

Loss of Grey White Differentiation (35% vs. 0%, p = .020)

Alteplase > Placebo (1)

4

0-90 Min

Abnormal Baseline CT (62% vs. 32%, p = .020)

Alteplase > Placebo (5)

4

91-180 Min

Hyperintense Artery Sign (24% vs. 3%, p = .025)

Placebo > Alteplase (3)

Old Lesion Volume (3.1 ± 7.2 vs. .35 ± 1.6, p = .025)