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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Comparing outcomes from tailored meta-analysis with outcomes from a setting specific test accuracy study using routine data of faecal calprotectin testing for inflammatory bowel disease

Fig. 2

ROC plot of studies reporting sensitivity and specificity of FC testing for IBD at 50 μg/g (Mahalanobis distance method). The applicable region for primary care is defined by the test positive rate (dashed line) and by test positive rate plus prevalence (trapezium) from THIN data defines the area of sensitivity and specificity that is compatible with UK primary care practices. Included studies using the Mahalanobis distance method (Carroccio 2003 [14], Oyaert 2014 [21], Oyaert 2017 [17], Boyd 2016 [13], Alrubaiy 2012 [12], DeSloovere 2017 [11], Conroy 2018 [10], El Badry 2010 [15], and Caviglia 2014 [9]) had closer ‘statistical distance’ to the applicable region than rejected studies (Labaere 2014 [17], Li 2006 [18], Hogberg 2017 [16], Mowat 2016 [19] and Tan 2016 [22])

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BMC Medical Research Methodology

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