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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: The value of time-dependent risk predictions in a screening context - a comprehensive simulation analysis validated on German cancer registry data

Fig. 1

a Showcase risk distribution over time, dependent on r and cvmr. Cvmr: coefficient of variation; r: Pearson correlation coefficient. b Visualization of decision strategies. (1) cumulative approach / CA: interval-specific risks (dark blue bars) are added up (dashed arrows): if the sum exceeds the chosen threshold, a screening examination is done. (2) approach with interval-specific reevaluation / CAIR: interval-specific risks are added up (dashed arrows) until the chosen threshold is reached, leading to a screening examination (cumulation process according to high threshold: dark blue bars; cumulation process according to low threshold: light blue bars). (3) interval-specific approach / ISA: if an interval-specific risk (dark blue bars) exceeds the threshold, a screening examination is done. Cvmr: coefficient of variation; r: Pearson correlation coefficient

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