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Table 1 Brief details of selected RCTs

From: Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs

RCT

Sample size

Outcomes

Interventions (test,control)

WAT

\(N=126\)

OHS at 6w, 3m, 6m, 12m (primary)

RSA, THA

DRAFFT

\(N=461\)

PRWE at 3m, 6m, 12m (primary)

Plate, Wire

WOLLF

\(N=460\)

DRI at 3m, 6m, 9m, 12m (primary)

NPWT, Standard

FASHION

\(N=348\)

iHOT-33 6m, 12m (primary)

Surgery, PHT

CSAW

\(N=210\)

OSS at 6m (primary), 12m

ASAD, AMSR

FIXDT

\(N=321\)

DRI at 3m, 6m (primary), 12m

Plate, Nail

TOPKAT

\(N=528\)

OKS at 2m, 1y, 2y, 3y, 4y, 5y (primary)

PKR, TKR