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Fig. 4 | BMC Medical Research Methodology

Fig. 4

From: Joint analysis of PK and immunogenicity outcomes using factorization model − a powerful approach for PK similarity study

Fig. 4

Comparison of actual GMR estimated from factorization model and ANOVA. a: correlation coefficient of ADA and covariate = 0.1; b: correlation coefficient of ADA and covariate = 0.3; c: correlation coefficient of ADA and ln(PK) = − 0.3; d: correlation coefficient of ADA and ln(PK) = − 0.5. Note: (c) and (d) are different presentations of (a) and (b). In the PK parameter data generation, assumed GMR = 0.95, CV = 0.4 and total sample size = 130

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BMC Medical Research Methodology

ISSN: 1471-2288

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