Table 2 Examples of stratified adaptive Bryant & Day (SABD) design (ESSRiTj and PETRiTj correspond to ESS (pRi−,pTj−,pRi+,pTj+) and PET (pRi−,pTj−,pRi+,pTj+), respectively)
Hypotheses | Parameters | Operating characteristics | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
pR0 | pR1− pR1+ | pT0 | pT1− pT1+ | kR1− kR1+ | kT1− kT1+ | N1− N1+ | kRe+ kTe+ | Ne+ | kR− kR+ | kT− kT+ | N− N+ | Attained αR / αT / 1- β | max (ESSR0T1,ESSR1T0) | min (PETR0T1,PETR1T0) |
0.70 | 0.90 0.90 | 0.70 | 0.90 0.90 | 8 8 | 8 8 | 10 10 | 29 29 | 35 | 29 27 | 29 27 | 35 32 | 0.094 / 0.094 / 0.800 | 42.5 | 0.415 |
0.30 | 0.60 0.60 | 0.60 | 0.90 0.90 | 4 4 | 7 7 | 9 9 | 10 16 | 21 | 11 8 | 18 13 | 23 16 | 0.094 / 0.093 / 0.800 | 25.7 | 0.554 |
0.10 | 0.40 0.40 | 0.60 | 0.80 0.90 | 3 2 | 12 7 | 17 9 | 4 13 | 16 | 7 3 | 26 9 | 35 10 | 0.087 / 0.096 / 0.800 | 32.1 | 0.580 |