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Table 7 Percentage reduction in cumulative incidence (2018–2030) (EHE plan compared to baseline intervention§)

From: Evaluating the sensitivity of jurisdictional heterogeneity and jurisdictional mixing in national level HIV prevention analyses: context of the U.S. ending the HIV epidemic plan

Scenario no. ➔ (reference scenario)

S5

(ref S1§)

S6

(ref S2§)

S7

(ref s3§)

S8

(ref S4§)

S13

(ref S9§)

S14

(ref S10§)

S15

(ref S11§)

S16 (ref S12§)

Care assumption ➔

Homogeneity in care across jurisdictions*

Heterogeneity in care across jurisdictions**

Mixing assumption ➔

No-mixing

Mixing level 1

Mixing level 2

Mixing level 3

No-mixing

Mixing level 1

Mixing level 2

Mixing level 3

Risk group

Jurisdiction  type

All

National

−24%

− 27%

− 30%

− 30%

− 30%

−31%

− 33%

−33%

EHE

−41%

− 40%

−38%

− 40%

−45%

− 44%

−41%

− 41%

Non-EHE

−5%

−14%

− 24%

− 23%

− 9%

− 15%

− 24%

−25%

HM

National

− 23%

− 24%

− 27%

− 27%

− 25%

− 27%

− 30%

− 30%

EHE

−36%

− 35%

− 34%

− 37%

− 40%

− 39%

− 37%

− 37%

Non-EHE

−4%

−12%

− 22%

− 20%

− 9%

− 15%

− 25%

− 25%

HF

National

−24%

− 25%

− 28%

− 28%

− 25%

−27%

−30%

− 30%

EHE

−38%

−38%

− 36%

− 38%

− 43%

− 42%

− 40%

−39%

Non-EHE

−3%

− 12%

−21%

− 20%

− 8%

− 14%

− 22%

− 23%

MSM

National

−25%

− 27%

− 31%

−31%

− 32%

− 33%

−35%

− 35%

EHE

− 43%

−42%

− 40%

− 41%

−47%

− 45%

−42%

− 41%

Non-EHE

−5%

− 14%

− 25%

− 24%

− 10%

−16%

− 25%

− 26%

  1. HM Heterosexual males, HF Heterosexual females, MSM Men who have sex with men
  2. National: aggregate of all EHE and non-EHE jurisdictions; EHE: aggregate of all EHE jurisdictions; Non-EHE: aggregate of all non-EHE jurisdictions;
  3. % reduction in cumulative incidence in EHE plan scenarios compared to its corresponding baseline scenario§ and calculated as 100 × (EHE plan scenario-baseline scenario)/ baseline scenario)
  4. § Scenarios 1 to 4 and 9 to 12 keep care metrics (HIV-diagnosis rate, care-drop-out rate, and PrEP coverage) fixed at the 2018 baseline values for the full duration of the simulation
  5. Scenarios 5 to 8 and 13 to 16 scale-up care metrics (HIV-diagnosis rate, care-drop-out rate, and PrEP coverage) to reach EHE targets by 2025 for EHE jurisdictions and by 2030 for non-EHE jurisdictions
  6. * Scenarios 5 to 8 and 1 to 4 assume jurisdictional homogeneity
  7. ** Scenarios 9 to 12 and 13 to 16 assume jurisdictional heterogeneity