Table 1 Comparison of the Covidicus and Recovery trials based on the Pocock criteria of population homogeneity
From: Challenges of using external data in clinical trials- an illustration in patients with COVID-19
Criteria | Covidicus | Recovery |
|---|---|---|
Treatment | High DXM | Low DXM |
Eligibility | Age>18 | No age limit |
Treatment evaluation | Death at day 28 and 60 | Death at day 28 |
Characteristics | ||
Age (years, mean ± standard deviation) | 66 ± 11 | 59 ± 13 |
Male sex | 80% | 73% |
Comorbities | 80% | 49% |
Organisation | France | UK |
Selection | April, 20- January, 21 | March-June, 20 |