Table 3 Comparison of treatment groups in each trial, before and after weighting. SoC: Standard of Care; DXM: dexamethasone
From: Challenges of using external data in clinical trials- an illustration in patients with COVID-19
Group | SoC | High DXM | High DXM weighted | Low DXM |
|---|---|---|---|---|
Age, mean ± SD | 65.2 ± 11.0 | 66.1 ± 10.7 | 58.8 ± 10.7 | 58.8 ± 11.3 |
Male sex, % | 72.5% | 80.4% | 72.0% | 72.0% |
Comorbidities, % | 74.3% | 70.1% | 49.0% | 49.0% |