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Table 6 A comparison with a previous review of the inclusion of randomisation factors in the analysis

From: A systematic review of randomisation method use in RCTs and association of trial design characteristics with method selection

Study characteristic

Kahan review (2010)

Our results (2019)

Total Trials using at least one balancing factor

41

247

  Centre as balancing factor

35 / 41 (85%)

80 / 247 (32%)

  At least one patient level prognostic factor

24 / 41 (59%)

189 / 247 (77%)

Adjusted for All balancing variables in analysis

14 / 41 (34%)

147 / 247 (60%)

Balanced on centre and adjusted for centre

13 / 35 (37%)

33 / 80 (41%)

Balanced on prognostic factor and adjusted for all in analysis

7 / 24 (29%)

145 / 189 (77%)

  1. Unless otherwise specified, the table reports the number of studies along with column percentages