Table 1 Patient characteristics in the base population
Characteristic | Transfusion | No transfusion | p |
|---|---|---|---|
(n = 662) | (n = 5479) | ||
Demographics | |||
Male, n (%) | 406 (61.3) | 2835 (51.7) | < 0.001 |
Age > 75, years, n(%) | 127 (19.2) | 831 (15.2) | 0.0071 |
Smoking, n (%) | 78 (11.8) | 547 (10.0) | 0.148 |
BMI, kg/m2, mean(SD) | 22.57 (3.39) | 23.56 (3.46) | < 0.001 |
Comorbidity, n (%) | |||
Hypertension | 291 (44.0) | 2768 (50.5) | 0.0014 |
Coronary heart disease | 70 (10.6) | 565 (10.3) | 0.834 |
Diabetes | 84 (12.7) | 693 (12.6) | 0.976 |
Stroke | 5 (0.8) | 84 (1.5) | 0.114 |
COPD | 8 (1.2) | 55 (1.0) | 0.621 |
ASA score ≥ 3, n (%) | 268 (40.5) | 1250 (22.8) | < 0.0001 |
Preoperative laboratory test | |||
Albumin < 35 g/L, n (%) | 264 (39.9) | 707 (12.9) | < 0.0001 |
High creatininea, n (%) | 86 (13.0) | 523 (9.5) | 0.0051 |
WBC count > 10 × 109/L, n (%) | 76 (11.5) | 483 (8.8) | 0.0244 |
Hemoglobin, g/dL, mean(SD) | 11.0 (29.7) | 13.5 (22.55) | < 0.001 |
Intraoperative feature, n (%) | |||
Operation time ≥ 3 h | 408 (65.2) | 1068 (20.9) | < 0.0001 |
Bleeding volume ≥ 500 mL | 251 (37.9) | 115 (2.1) | < 0.0001 |
Postoperative feature, n (%) | |||
ICU admission after surgery | 147 (22.2) | 436 (8.0) | < 0.0001 |
Postoperative outcome, n (%) | |||
Complications | 102 (15.41) | 226 (4.12) | < 0.0001 |
Ischemic events | 22 (3.32) | 26 (0.47) | < 0.0001 |
Infection | 76 (11.48) | 170 (3.10) | < 0.0001 |
Others | 19 (2.87) | 48 (0.88) | < 0.0001 |
Death | 39 (5.89) | 29 (0.53) | < 0.0001 |