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Table 1 Model reporting criteria that prediction studies should report to enable external validation

From: External validation of existing dementia prediction models on observational health data

Category

Reporting criteria

Description

Population settings

Target population definition

Definition or description of the population for which predictions are made.

Index date

Date at which a patient qualifies for inclusion in the target population.

Time-at-risk

Time window in which a model’s predictions are valid relative to the index date.

Outcome definition

Definition or description of the outcome to be predicted during the time-at-risk.

Statistical analysis settings

Prediction method

Prediction methods in this study are limited to logistic regression and Cox proportional hazard for predicting a binary outcome.

Predictor definitions

Predictor descriptions or definitions in terms of data source codes.

Predictor time window

Time window in which the predictor is assessed. In a special case, a predictor can be assessed in a time window all time prior to index, often reported as “a history of …” using all available prior data of a person.

Model specifications

The prediction model, e.g., parameters to construct the model given a prediction method. Alternatively, a risk calculator or nomogram could be reported.

We also distinguish here between fully and partially specified models. For example, if no intercept is reported in the case of a logistic regression model, we are still able to construct a simple risk stratification model using only coefficient values. However, this method does not consider the baseline risk of the original model and (re-)calibration will not be assessed.