Fig. 2
From: Evaluation of two-stage designs of Phase 2 single-arm trials in glioblastoma: a systematic review
Results of design input parameters and sample size calculation output from reviews of Phase 2 single-arm two-stage designs in glioblastoma. GBM: glioblastoma, PFS6: progression-free survival at 6 months, Key info: key input parameters for two-stage design, Right SS: did two-stage sample size calculation be appropriately implanted? and HCR: did the reference of historical control rate be provided?, all key input and output information as well as reference of historical control rates provided (Yes, No)?, and (11) did the trial be stopped (Yes, No)?