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Table 1 Baseline characteristics for each race and sex group in training/internal validation dataset and external validation dataset

From: Comparison of State-of-the-Art Neural Network Survival Models with the Pooled Cohort Equations for Cardiovascular Disease Risk Prediction

 

Overall

White male

Black male

White female

Black female

P-value

Training/internal validation dataset

 N

23216

8644

1354

10719

2499

 

 Number of Events, n (%)

3705 (16.0)

1788 (20.7)

300 (22.2)

1217 (11.4)

400 (16.0)

 

 Age (year), mean (SD)

57.8 (9.6)

58.0 (9.6)

57.3 (9.5)

58.0 (9.7)

56.4 (9.3)

 < 0.001

 SBP (mm Hg), mean (SD)

127.1 (21.0)

127.2 (19.5)

131.8 (21.5)

125.5 (21.6)

130.8 (22.7)

 < 0.001

 HDL-C (mg/dL), mean (SD)

51.6 (16.4)

43.8 (12.7)

49.7 (16.0)

56.8 (16.5)

57.5 (16.4)

 < 0.001

 TOTCHL (mg/dL), mean (SD)

217.8 (43.0)

212.1 (39.9)

208.6 (44.4)

223.9 (43.8)

216.0 (45.4)

 < 0.001

 HXDIAB, n (%)

1069 (4.6)

295 (3.4)

175 (12.9)

294 (2.7)

305 (12.2)

 < 0.001

 Smoker, n (%)

6035 (26.0)

2294 (26.5)

441 (32.6)

2723 (25.4)

577 (23.1)

 < 0.001

 RXHYP, n (%)

7326 (31.6)

2226 (25.8)

707 (52.2)

2951 (27.5)

1442 (57.7)

 < 0.001

MESA external validation dataset

 N

4259

1194

799

1284

982

 

 Number of Events, n (%)

331 (7.8)

104 (8.7)

85 (10.6)

79 (6.2)

63 (6.4)

 

 Age (year), mean (SD)

61.6 (9.6)

61.9 (9.6)

61.5 (9.6)

61.5 (9.6)

61.3 (9.4)

0.446

 SBP (mmHg), mean (SD)

126.3 (21.0)

123.7 (18.3)

130.0 (19.2)

121.8 (21.4)

132.4 (22.8)

 < 0.001

 HDL-C (mm/dL), mean (SD)

52.2 (15.5)

45.2 (12.1)

46.5 (12.5)

58.8 (15.8)

56.9 (15.6)

 < 0.001

 TOTCHL (mm/dL), mean (SD)

193.3 (35.7)

189.2 (34.4)

182.0 (34.6)

202.3 (34.4)

195.7 (36.5)

 < 0.001

 HXDIAB, n (%)

354 (8.3)

57 (4.8)

117 (14.6)

51 (4.0)

129 (13.1)

 < 0.001

 Smoker, n (%)

628 (14.7)

137 (11.5)

166 (20.8)

160 (12.5)

165 (16.8)

 < 0.001

 RXHYP, n (%)

1676 (39.4)

389 (32.6)

370 (46.3)

402 (31.3)

515 (52.4)

 < 0.001

  1. Abbreviations: SD standard deviation, SBP systolic blood pressure, HDL-C high density cholesterol, TOTCHL total cholesterol, HXDIAB history of diabetes, RXHYP history of hypertension