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Table 3 Results of the Bayesian model using different priors for RT-PCR specificity and sensitivity for addressing misclassification bias

From: Addressing misclassification bias in vaccine effectiveness studies with an application to Covid-19

Study

 Sp/Se

Median (95% PrI)

OR (95% PrI)

VE (95% PrI)

Perfect classification

Sp

1.000

0.075 (0.057-0.096)

92.5 (90.4-94.3)

Se

1.000

Kostoulas 2021

Sp

0.990 (0.980-1.000)

0.036 (0.009-0.063)

96.4 (93.7-99.1)

Se

0.680 (0.630-0.730)

Stærk-Østergaard 2021

Sp

0.999 (0.999-1.000)

0.070 (0.050-0.090)

93.0 (91.0-95.0)

Se

0.957 (0.928-0.984)

  1. Se=sensitivity; Sp=specificity; OR=Odds Ratio; PrI=probability interval; VE=vaccine effectiveness