Table 2 Mean predictive performance of PLANNCR extended for disease progression (event of interest) tuned with Brier score or AUC at 5 years. The 95% confidence intervals are provided in parentheses based on 100 validation datasets

Brier score at 2 years

0.208 (0.198 - 0.220)

0.214 (0.201 - 0.226)

Brier score at 5 years

0.228 (0.221 - 0.235)

0.231 (0.225 - 0.236)

Brier score at 10 years

0.238 (0.229 - 0.247)

0.240 (0.234 - 0.247)

AUC at 2 years

0.661 (0.637 - 0.688)

0.659 (0.640 - 0.683)

AUC at 5 years

0.652 (0.612 - 0.689)

0.660 (0.633 - 0.685)

AUC at 10 years

0.629 (0.576 - 0.681)

0.631 (0.582 - 0.678)

Miscalibration at 2 years

0.008 (0.003 - 0.017)

0.013 (0.006 - 0.022)

Miscalibration at 5 years

0.003 (0.001 - 0.008)

0.008 (0.004 - 0.014)

Miscalibration at 10 years

0.002 (0.000 - 0.008)

0.004 (0.001 - 0.009)