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Table 5 Comparison of trial characteristics across the real and synthetic datasets

From: A method for generating synthetic longitudinal health data

 

Real

n = 75,660

Synthetic

n = 75,660

SMD

Age

  

0.078

 Mean (SD)

43.32 (17.87)

44.79 (19.83)

 

 Median (IQR)

42.00 [27.00]

43.00 [30.00]

 

Sex n (%)

  

0.029

 Male

38,623 (51.0)

39,711 (52.5)

 

 Female

37,037 (49.0)

35,949 (47.5)

 

Elixhauser

  

0.055

 Mean (SD)

0.96 (1.58)

1.05 (1.63)

 

 Median (IQR)

0.00 [1.00]

0.00 [2.00]

 

ALT

  

0.099

 Mean (SD)

31.67 (63.90)

40.72 (111.92)

 

 Median (IQR)

24.00 [18.00]

26.00 [19.00]

 

eGFR

  

0.112

 Mean (SD)

85.82 (23.56)

83.11 (25.05)

 

 Median (IQR)

87.00 [41.00]

84.00 [38.00]

 

HCT

  

0.291

 Mean (SD)

0.42 (0.05)

0.41 (0.06)

 

 Median (IQR)

0.42 [0.05]

0.41 [0.06]

 

CACS-RIW

  

0.002

 Mean (SD)

0.05 (0.07)

0.05 (0.07)

 

 Median (IQR)

0.03 [0.03]

0.03 [0.03]

 

RIW

  

0.002

 Mean (SD)

1.40 (2.73)

1.40 (2.40)

 

 Median (IQR)

0.77 [0.82]

0.81 [0.84]

 

Opioid Utilization (%)

 Morphine

1758 (2.3)

2649 (3.5)

0.070

 Oxycodone

73,902 (97.7)

73,011 (96.5)

 

Antidepressant Use

28,224 (37.3)

29,651 (39.2)

0.039