Skip to main content

Table 4 Well-approximated type I error rates and power observed when controlling the well-approximated FWER below 5%

From: Practical basket design for binary outcomes with control of family-wise error rate

  

Subpopulation j

Scenario

Method

1

2

3

4

1

Independent

0%

0%

0%

0%

BHM-weak

1%

1%

1%

1%

BHM-strong

1%

1%

1%

1%

2

Independent

0%

0%

0%

54%

BHM-weak

1%

1%

2%

67%

BHM-strong

2%

3%

4%

65%

3

Independent

0%

0%

61%

53%

BHM-weak

1%

1%

73%

67%

BHM-strong

5%

7%

83%

76%

4

Independent

0%

57%

61%

53%

BHM-weak

1%

71%

74%

68%

BHM-strong

10%

85%

91%

85%

5

Independent

57%

57%

61%

53%

BHM-weak

72%

71%

75%

68%

BHM-strong

91%

90%

95%

90%

  1. BHM Bayesian hierarchical models
  2. Type I error rates are shown in boldface; values not presented in bold indicate power