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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy

Fig. 1

Examples of subgroup divisions. The level of Biomarker1 increases from top to bottom, and the level of Biomarker2 increases from left to right. The high-efficacy subgroups and low-efficacy subgroups are represented in green and blue, respectively. A Five possible subgroup divisions when K = 2 and J = 2. B Four possible subgroup divisions when K = 3 and J = 4, and there are 34 divisions in total

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BMC Medical Research Methodology

ISSN: 1471-2288

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