Table 4 Empirical family-wise error rate (FWER) for the likelihood ratio test (LRT), normal approximation, proportional reporting ratio (PRR), and reporting odds ratio while using either Max-Stat or Benjamini-Hochberg (BH) method for adjustment of multiple testing when all null hypotheses are true. The inference methods were applied at \(\alpha =0.05\). The result is based on 500,000 simulation runs based on the FAERS dataset regarding sex for different sample sizes when there is no difference between host factor groups (\(\Delta =0\))

From: Statistical methods for exploring spontaneous adverse event reporting databases for drug-host factor interactions