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Table 3 The variance in estimation of the comparison of interest, \(\text {Var}(\hat{\mu }_{N,E})\), using the best connecting trial when the comparison of interest is N to E compared to the variance using a direct trial of N to E

From: Connecting a disconnected trial network with a new trial: optimizing the estimation of a comparative effect in a network meta-analysis

 

\(\text {Var}(\hat{\mu }_{N,E})\)

n

Best Connecting Trial

Direct Trial

6

DJ-E

2.8260

2.8397

8

H-E

2.1221

2.1298

10

H-E

1.6988

1.7038

12

H-E

1.4166

1.4199

14

H-E

1.2151

1.2170

16

H-E

1.0639

1.0649

18

H-E

0.9463

0.9466

20

N-E

0.8519

0.8519

50

N-E

0.3408

0.3408

100

N-E

0.1704

0.1704

200

N-E

0.0852

0.0852

500

N-E

0.0341

0.0341

1000

N-E

0.0170

0.0170

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BMC Medical Research Methodology

ISSN: 1471-2288

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