From: Neutral theory: applicability and neutrality of clinical study endpoints where a disease-specific instrument is available
Indicators in a clinical study
Indicators within DSS
Indicators outside DSS
Included
Overlap (a)
Redundant (b)
Excluded
Missing (c)
Irrelevant (d)
Total
(a + c)
(b + d)
Neutrality (accuracy)
Sensitivity: a/a + c
Specificity: d/b + d