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Data analysis, statistics and modelling

Section edited by Chiu-Hsieh (Paul) Hsu

This section considers manuscripts that investigate how statistical techniques can impact study results along with manuscripts that propose new statistical methods that have an application in medical research.

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  1. Content type: Research article

    We evaluate three methods for competing risks analysis with time-dependent covariates in comparison with the corresponding methods with time-independent covariates.

    Authors: Inga Poguntke, Martin Schumacher, Jan Beyersmann and Martin Wolkewitz on behalf of COMBACTE-MAGNET Consortium

    Citation: BMC Medical Research Methodology 2018 18:79

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  2. Content type: Research article

    Multilevel models for non-normal outcomes are widely used in medical and health sciences research. While methods for interpreting fixed effects are well-developed, methods to quantify and interpret random clus...

    Authors: Thomas J. Glorioso, Gary K. Grunwald, P. Michael Ho and Thomas M. Maddox

    Citation: BMC Medical Research Methodology 2018 18:74

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  3. Content type: Research article

    There are an increasing number of geo-coded information streams available which could improve public health surveillance accuracy and efficiency when properly integrated. Specifically, for zoonotic diseases, k...

    Authors: C. Rotejanaprasert, A. Lawson, H. Rossow, J. Sane, O. Huitu, H. Henttonen and V. J. Del Rio Vilas

    Citation: BMC Medical Research Methodology 2018 18:72

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  4. Content type: Research article

    Recently, the intervention calculus when the DAG is absent (IDA) method was developed to estimate lower bounds of causal effects from observational high-dimensional data. Originally it was introduced to assess...

    Authors: Vahé Asvatourian, Clélia Coutzac, Nathalie Chaput, Caroline Robert, Stefan Michiels and Emilie Lanoy

    Citation: BMC Medical Research Methodology 2018 18:67

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  5. Content type: Research article

    Few studies have compared methods to correct for retest effects or practice effects in settings where an acute event could influence test performance, such as major surgery. Our goal in this study was to evalu...

    Authors: Annie M. Racine, Yun Gou, Tamara G. Fong, Edward R. Marcantonio, Eva M. Schmitt, Thomas G. Travison, Sharon K. Inouye and Richard N. Jones

    Citation: BMC Medical Research Methodology 2018 18:69

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  6. Content type: Research article

    Network meta-analysis (NMA) allows for the estimation of comparative effectiveness of treatments that have not been studied in head-to-head trials; however, relative treatment effects for all interventions can...

    Authors: Susanne Schmitz, Áine Maguire, James Morris, Kai Ruggeri, Elisa Haller, Isla Kuhn, Joy Leahy, Natalia Homer, Ayesha Khan, Jack Bowden, Vanessa Buchanan, Michael O’Dwyer, Gordon Cook and Cathal Walsh

    Citation: BMC Medical Research Methodology 2018 18:66

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  7. Content type: Research article

    A new patient-reported health measurement model has been developed to quantify descriptions of health states. Known as the multi-attribute preference response (MAPR) model, it is based on item response theory....

    Authors: Catharina G. M. Groothuis-Oudshoorn, Edwin R. van den Heuvel and Paul F. M. Krabbe

    Citation: BMC Medical Research Methodology 2018 18:62

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  8. Content type: Research article

    In pharmacoepidemiology, the prescription preference-based instrumental variables (IV) are often used with linear models to solve the endogeneity due to unobserved confounders even when the outcome and the end...

    Authors: Babagnidé François Koladjo, Sylvie Escolano and Pascale Tubert-Bitter

    Citation: BMC Medical Research Methodology 2018 18:61

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  9. Content type: Research article

    Log-binomial and robust (modified) Poisson regression models are popular approaches to estimate risk ratios for binary response variables. Previous studies have shown that comparatively they produce similar po...

    Authors: Wansu Chen, Lei Qian, Jiaxiao Shi and Meredith Franklin

    Citation: BMC Medical Research Methodology 2018 18:63

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  10. Content type: Research article

    When profiling multiple health care providers, adjustment for case-mix is essential to accurately classify the quality of providers. Unfortunately, misclassification of provider performance is not uncommon and...

    Authors: Timo B. Brakenhoff, Kit C. B. Roes, Karel G. M. Moons and Rolf H. H. Groenwold

    Citation: BMC Medical Research Methodology 2018 18:54

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  11. Content type: Research article

    Decisions about which subgroup of chronic hepatitis C (CHC) patients should be treated with direct acting anti-viral agents (DAAs) have economic importance due to high drug prices. Treat-all DAA strategies for...

    Authors: Rodolfo Castro, Louise Crathorne, Hugo Perazzo, Julio Silva, Chris Cooper, Jo Varley-Campbell, Daniel Savignon Marinho, Marcela Haasova, Valdilea G. Veloso, Rob Anderson and Chris Hyde

    Citation: BMC Medical Research Methodology 2018 18:53

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  12. Content type: Research article

    Motivational Interviewing (MI), Brief Advice (BA) and Health Education (HE) are established smoking cessation induction methods for smokers with low desire to quit. Although randomized controlled trials (RCT’s...

    Authors: Majid Bani-Yaghoub, Abdellatif Elhomani and Delwyn Catley

    Citation: BMC Medical Research Methodology 2018 18:52

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  13. Content type: Software

    Joint modelling of longitudinal and time-to-event outcomes has received considerable attention over recent years. Commensurate with this has been a rise in statistical software options for fitting these models...

    Authors: Graeme L. Hickey, Pete Philipson, Andrea Jorgensen and Ruwanthi Kolamunnage-Dona

    Citation: BMC Medical Research Methodology 2018 18:50

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  14. Content type: Research article

    In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate es...

    Authors: Shahina Rahman, Maja von Cube, Martin Schumacher and Martin Wolkewitz

    Citation: BMC Medical Research Methodology 2018 18:49

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  15. Content type: Debate

    Randomised trials with long-term follow-up can provide estimates of the long-term effects of health interventions. However, analysis of long-term outcomes in randomised trials may be complicated by problems wi...

    Authors: Robert D. Herbert, Jessica Kasza and Kari Bø

    Citation: BMC Medical Research Methodology 2018 18:48

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