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  1. The Community Reintegration of Service Members (CRIS) is a new measure of community reintegration developed to measure veteran's participation in life roles. It consists of three sub-scales: Extent of Particip...

    Authors: Linda J Resnik, Melissa A Clark and Matthew Borgia
    Citation: BMC Medical Research Methodology 2011 11:98
  2. How overall physical activity relates to specific activities and how reported activity changes over time may influence interpretation of observed associations between physical activity and health. We examine t...

    Authors: Miranda EG Armstrong, Benjamin J Cairns, Jane Green, Gillian K Reeves and Valerie Beral
    Citation: BMC Medical Research Methodology 2011 11:97
  3. When the mortality among a cancer patient group returns to the same level as in the general population, that is, the patients no longer experience excess mortality, the patients still alive are considered "sta...

    Authors: Therese ML Andersson, Paul W Dickman, Sandra Eloranta and Paul C Lambert
    Citation: BMC Medical Research Methodology 2011 11:96
  4. Response rate (RR) alone may be insensitive to drug activity in phase II trials. Early progressive disease (EPD) could improve sensitivity as well as increase stage I stopping rates. This study compares the pr...

    Authors: John R Goffin, Greg R Pond and Dongsheng Tu
    Citation: BMC Medical Research Methodology 2011 11:95
  5. Estimating the required sample size and statistical power for a study is an integral part of study design. For standard designs, power equations provide an efficient solution to the problem, but they are unava...

    Authors: Benjamin F Arnold, Daniel R Hogan, John M Colford Jr and Alan E Hubbard
    Citation: BMC Medical Research Methodology 2011 11:94
  6. The Edinburgh Postnatal Depression Scale (EPDS) has been proposed as a one-dimensional instrument and used as a single 10-item scale. This might be considered questionable since repeated psychometric studies h...

    Authors: Michael E Reichenheim, Claudia L Moraes, Alessandra SD Oliveira and Gustavo Lobato
    Citation: BMC Medical Research Methodology 2011 11:93
  7. Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth o...

    Authors: Peter Bragge, Ornella Clavisi, Tari Turner, Emma Tavender, Alex Collie and Russell L Gruen
    Citation: BMC Medical Research Methodology 2011 11:92
  8. The anti-TNF inhibitor, etanercept is administered as a once or twice weekly subcutaneous injection for the treatment of rheumatoid arthritis, psoriasis, ankylosing spondylitis, psoriatic arthritis and juvenil...

    Authors: Alan G Wade, Gordon M Crawford, Neil Pumford, Volker Koscielny, Susan Maycock and Alex McConnachie
    Citation: BMC Medical Research Methodology 2011 11:91
  9. Investigating the size and mechanisms of the placebo response in clinical trials have relied on experimental procedures that simulate the double-blind randomized placebo-controlled design. However, as the conv...

    Authors: Paul Enck, Sibylle Klosterhalfen and Stephan Zipfel
    Citation: BMC Medical Research Methodology 2011 11:90
  10. Sample size calculations require effect size estimations. Sometimes, effect size estimations and standard deviation may not be readily available, particularly if efficacy is unknown because the intervention is...

    Authors: Helen M Kirkby, Sue Wilson, Melanie Calvert and Heather Draper
    Citation: BMC Medical Research Methodology 2011 11:89
  11. Many studies have investigated racial/ethnic disparities in medication non-adherence in patients with type 2 diabetes using common measures such as medication possession ratio (MPR) or gaps between refills. Al...

    Authors: Mulugeta Gebregziabher, Cheryl P Lynch, Martina Mueller, Gregory E Gilbert, Carrae Echols, Yumin Zhao and Leonard E Egede
    Citation: BMC Medical Research Methodology 2011 11:88
  12. Several disease-specific questionnaires to measure pain and disability in patients with neck pain have been translated. However, a simple translation of the original version doesn't guarantee similar measureme...

    Authors: Jasper M Schellingerhout, Martijn W Heymans, Arianne P Verhagen, Henrica C de Vet, Bart W Koes and Caroline B Terwee
    Citation: BMC Medical Research Methodology 2011 11:87
  13. Competing risks methodology allows for an event-specific analysis of the single components of composite time-to-event endpoints. A key feature of competing risks is that there are as many hazards as there are ...

    Authors: Arthur Allignol, Martin Schumacher, Christoph Wanner, Christiane Drechsler and Jan Beyersmann
    Citation: BMC Medical Research Methodology 2011 11:86
  14. We determined the diagnostic accuracy of the Edinburgh Claudication Questionnaire (ECQ) in 1st generation Black African-Caribbean UK migrants as previous diagnostic questionnaires have been found to be less accur...

    Authors: Philip C Bennett, Gregory YH Lip, Stanley Silverman, Andrew D Blann and Paramjit S Gill
    Citation: BMC Medical Research Methodology 2011 11:85
  15. Gastric Emptying Scintigraphy (GES) at intervals over 4 hours after a standardized radio-labeled meal is commonly regarded as the gold standard for diagnosing gastroparesis. The objectives of this study were: ...

    Authors: Qingjiang Hou, Zhiyue Lin, Reginald Dusing, Byron J Gajewski, Richard W McCallum and Matthew S Mayo
    Citation: BMC Medical Research Methodology 2011 11:84
  16. The Charlson comorbidity index is often used to control for confounding in research based on medical databases. There are few studies of the accuracy of the codes obtained from these databases.

    Authors: Sandra K Thygesen, Christian F Christiansen, Steffen Christensen, Timothy L Lash and Henrik T Sørensen
    Citation: BMC Medical Research Methodology 2011 11:83
  17. We investigate whether the changing environment caused by rapid economic growth yielded differential effects for successive Taiwanese generations on 8 components of metabolic syndrome (MetS): body mass index (...

    Authors: Yu-Kang Tu, Kuo-Liong Chien, Victoria Burley and Mark S Gilthorpe
    Citation: BMC Medical Research Methodology 2011 11:82
  18. Maximizing response rates is critically important in order to provide the most generalizable and unbiased research results. High response rates reduce the chance of respondents being systematically different f...

    Authors: Joan M Griffin, Alisha Baines Simon, Erin Hulbert, John Stevenson, Joseph P Grill, Siamak Noorbaloochi and Melissa R Partin
    Citation: BMC Medical Research Methodology 2011 11:81
  19. In the randomized study of interferon beta-1b (IFN beta-1b) for multiple sclerosis (MS), it has usually been evaluated the simple annual relapse rate as the study endpoint. This study aimed to investigate the ...

    Authors: Makiko N Mieno, Takuhiro Yamaguchi and Yasuo Ohashi
    Citation: BMC Medical Research Methodology 2011 11:80
  20. Qualitative studies of participants' experiences in randomised clinical trials (RCTs) suggest that the psychosocial context of treatment in RCTs may be quite different to the psychosocial context of treatment ...

    Authors: Fiona Barlow, Clare Scott, Beverly Coghlan, Philippa Lee, Peter White, George T Lewith and Felicity L Bishop
    Citation: BMC Medical Research Methodology 2011 11:79
  21. In medical research, one common competing risks situation is the study of different types of events, such as disease recurrence and death. We focused on that situation but considered death under two aspects: "...

    Authors: Aurélien Belot, Laurent Remontet, Guy Launoy, Valérie Jooste and Roch Giorgi
    Citation: BMC Medical Research Methodology 2011 11:78
  22. Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of...

    Authors: Baoyue Li, Hester F Lingsma, Ewout W Steyerberg and Emmanuel Lesaffre
    Citation: BMC Medical Research Methodology 2011 11:77
  23. Energy-based surgical scalpels are designed to efficiently transect and seal blood vessels using thermal energy to promote protein denaturation and coagulation. Assessment and design improvement of ultrasonic ...

    Authors: Wiebke S Diestelkamp, Carissa M Krane and Margaret F Pinnell
    Citation: BMC Medical Research Methodology 2011 11:75
  24. Although previous studies using non- elderly groups have assessed the factorial invariance of the Center for Epidemiological Studies Depression Scale (CES-D) across different groups with the same social-cultur...

    Authors: Baoshan Zhang, Marjolein Fokkema, Pim Cuijpers, Juan Li, Niels Smits and Aartjan Beekman
    Citation: BMC Medical Research Methodology 2011 11:74
  25. The correspondence of satisfaction ratings between physicians and patients can be assessed on different dimensions. One may examine whether they differ between the two groups or focus on measures of associatio...

    Authors: Oliver Hirsch, Heidemarie Keller, Christina Albohn-Kühne, Tanja Krones and Norbert Donner-Banzhoff
    Citation: BMC Medical Research Methodology 2011 11:71
  26. Following the expansion of the European Union, there has been a large influx of Central and East European (CEE) migrants to the UK. CEE men who have sex with men (MSM) represent a small minority within this po...

    Authors: Alison R Evans, Graham J Hart, Richard Mole, Catherine H Mercer, Violetta Parutis, Christopher J Gerry, John Imrie and Fiona M Burns
    Citation: BMC Medical Research Methodology 2011 11:69
  27. Concern about the completeness of comorbidity information in hospital records has been raised as a limitation of using hospital discharge data for research. The aim of this study is to assess the impact of add...

    Authors: Jian Sheng Chen, Christine L Roberts, Judy M Simpson and Jane B Ford
    Citation: BMC Medical Research Methodology 2011 11:68
  28. In epidemiological studies explanatory variables are frequently subject to measurement error. The aim of this paper is to develop a Bayesian method to correct for measurement error in multiple continuous expos...

    Authors: Gabriela Espino-Hernandez, Paul Gustafson and Igor Burstyn
    Citation: BMC Medical Research Methodology 2011 11:67
  29. Confidence intervals (or associated standard errors) facilitate assessment of the practical importance of the findings of a health study, and their incorporation into a meta-analysis. For paired design studies...

    Authors: Karim F Hirji and Morten W Fagerland
    Citation: BMC Medical Research Methodology 2011 11:66
  30. Volunteering participants in disease studies tend to be healthier than the general population partially due to specific enrollment criteria. Using modeling to accurately predict outcomes of cohort studies enro...

    Authors: Millennia Foy, Xing Chen, Marek Kimmel and Olga Y Gorlova
    Citation: BMC Medical Research Methodology 2011 11:64
  31. For practical reasons it is not easy to obtain fasting samples in large population health surveys. Non-fasting triglyceride (Tg) values are difficult to interpret. The authors compared the accuracy of statisti...

    Authors: Jouko Sundvall, Jaana Leiviskä, Tiina Laatikainen, Markku Peltonen, Veikko Salomaa, Mauno Vanhala, Eeva Korpi-Hyövälti, Jukka Lauronen and Georg Alfthan
    Citation: BMC Medical Research Methodology 2011 11:63
  32. Minimising participant non-response in postal surveys helps to maximise the generalisability of the inferences made from the data collected. The aim of this study was to examine the effect of questionnaire len...

    Authors: Shannon Sahlqvist, Yena Song, Fiona Bull, Emma Adams, John Preston and David Ogilvie
    Citation: BMC Medical Research Methodology 2011 11:62
  33. Ambulatory blood pressure monitoring (ABPM) is increasingly used to measure blood pressure (BP) in research studies. We examined ease of use, comfort, degree of disturbance, reported adverse effects, factors a...

    Authors: Anthony J Viera, Kara Lingley and Alan L Hinderliter
    Citation: BMC Medical Research Methodology 2011 11:59
  34. Mixed effects logistic models have become a popular method for analyzing multicenter clinical trials with binomial data. However, the statistical properties of these models for testing homogeneity of odds rati...

    Authors: Zahra Bagheri, Seyyed Mohammad Taghi Ayatollahi and Peyman Jafari
    Citation: BMC Medical Research Methodology 2011 11:58
  35. Health related quality of life (HRQOL) has increasingly emphasized on cancer patients. The psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Can...

    Authors: Jin-xiang Cheng, Bo-lin Liu, Xiang Zhang, Yong-qiang Zhang, Wei Lin, Rui Wang, Yong-qin Zhang, Hong-ying Zhang, Li Xie and Jun-li Huo
    Citation: BMC Medical Research Methodology 2011 11:56
  36. Intention-to-treat (ITT) is the standard data analysis method which includes all patients regardless of receiving treatment. Although the aim of ITT analysis is to prevent bias due to prognostic dissimilarity,...

    Authors: Branko Miladinovic, Ambuj Kumar, Iztok Hozo and Benjamin Djulbegovic
    Citation: BMC Medical Research Methodology 2011 11:55
  37. During community epidemics, infections may be imported within hospital and transmitted to hospitalized patients. Hospital outbreaks of communicable diseases have been increasingly reported during the last deca...

    Authors: Nicolas Voirin, Sylvain Roche, Philippe Vanhems, Marine Giard, Sandra David-Tchouda, Béatrice Barret and René Ecochard
    Citation: BMC Medical Research Methodology 2011 11:53
  38. Currently, there is one Behçet's disease (BD) specific self reporting questionnaire developed and published in the literature, The Leeds BD-quality of life (QoL). We conducted a cross-cultural adaptation and v...

    Authors: Zahi Touma, Lilian Ghandour, Abla Sibai, Houry Puzantian, Ayad Hamdan, Omar Hamdan, Jeanine Menassa, Imad Uthman and Thurayya Arayssi
    Citation: BMC Medical Research Methodology 2011 11:52
  39. Previous research has documented heterogeneity in the effects of maternal education on adverse birth outcomes by nativity and Hispanic subgroup in the United States. In this article, we considered the risk of ...

    Authors: Jay S Kaufman, Richard F MacLehose, Elizabeth A Torrone and David A Savitz
    Citation: BMC Medical Research Methodology 2011 11:51
  40. Many studies compared the degree of concordance between adolescents' and parents' reports on family socioeconomic status (SES). However, none of these studies analyzed whether the degree of concordance varies ...

    Authors: Christy Pu, Nicole Huang and Yiing-Jenq Chou
    Citation: BMC Medical Research Methodology 2011 11:50
  41. Many previous studies have found seasonal patterns in birth outcomes, but with little agreement about which season poses the highest risk. Some of the heterogeneity between studies may be explained by a previo...

    Authors: Linn Beate Strand, Adrian G Barnett and Shilu Tong
    Citation: BMC Medical Research Methodology 2011 11:49

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