Table 2 Potential applications of a national asthma database.
From: A methodology to establish a database to study gene environment interactions for childhood asthma
Potential application | Resource |
|---|---|
Identification of genetically susceptible individuals for pharmacogenetic studies | DNA |
Identification of genetically susceptible individuals for environmental modification studies | DNA |
Characterisation of patterns of inhaled environmental hazards in children with asthma | Questionnaire and longitudinal component |
Validate a system to score asthma severity | All data |
Explore gene-environment interactions for subgroups, eg severe asthma, non-atopic asthma | Subgroups |
Audit standard of care between centres | Management + CACQ |
Identify associations between gene-environment interactions and natural history | Longitudinal study |
Confirm associations seen in secondary care study | Primary care study |