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  1. Correspondence

    Practical partnered research to improve weight loss among overweight/obese veterans: lessons from the trenches

    Obesity and obesity-related conditions, such as type 2 diabetes, are a major issue for Veteran health. Veterans Health Administration (VA) researchers and health systems leaders have worked separately and toge...

    Mona AuYoung, Laura J. Damschroder, Linda Kinsinger, Tannaz Moin and Caroline R. Richardson

    BMC Medical Research Methodology 2017 17:50

    Published on: 29 March 2017

  2. Research article

    The effect of postal questionnaire burden on response rate and answer patterns following admission to intensive care: a randomised controlled trial

    The effects of postal questionnaire burden on return rates and answers given are unclear following treatment on an intensive care unit (ICU). We aimed to establish the effects of different postal questionnaire...

    Robert Hatch, Duncan Young, Vicki Barber, David A Harrison and Peter Watkinson

    BMC Medical Research Methodology 2017 17:49

    Published on: 27 March 2017

  3. Research article

    Evaluation of AMSTAR to assess the methodological quality of systematic reviews in overviews of reviews of healthcare interventions

    Overviews of reviews (overviews) compile information from multiple systematic reviews (SRs) to provide a single synthesis of relevant evidence for decision-making. It is recommended that authors assess and rep...

    Michelle Pollock, Ricardo M. Fernandes and Lisa Hartling

    BMC Medical Research Methodology 2017 17:48

    Published on: 23 March 2017

  4. Research article

    Incorporating nonlinearity into mediation analyses

    Mediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent ...

    George J. Knafl, Kathleen A. Knafl, Margaret Grey, Jane Dixon, Janet A. Deatrick and Agatha M. Gallo

    BMC Medical Research Methodology 2017 17:45

    Published on: 21 March 2017

  5. Research article

    Methods for conceptualising ‘visual ability’ as a measurable construct in children with cerebral palsy

    Vision influences functioning and disability of children with cerebral palsy, so there is a growing need for psychometrically robust tools to advance assessment of children’s vision abilities in clinical pract...

    Belinda Deramore Denver, Margareta Adolfsson, Elspeth Froude, Peter Rosenbaum and Christine Imms

    BMC Medical Research Methodology 2017 17:46

    Published on: 21 March 2017

  6. Correspondence

    Implementation of clinical research trials using web-based and mobile devices: challenges and solutions

    With the increasing implementation of web-based, mobile health interventions in clinical trials, it is crucial for researchers to address the security and privacy concerns of patient information according to h...

    Roy Eagleson, Luis Altamirano-Diaz, Alex McInnis, Eva Welisch, Stefanie De Jesus, Harry Prapavessis, Meghan Rombeek, Jamie A. Seabrook, Teresa Park and Kambiz Norozi

    BMC Medical Research Methodology 2017 17:43

    Published on: 17 March 2017

  7. Research article

    Standardizing effect size from linear regression models with log-transformed variables for meta-analysis

    Meta-analysis is very useful to summarize the effect of a treatment or a risk factor for a given disease. Often studies report results based on log-transformed variables in order to achieve the principal assum...

    Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo and María José Sánchez

    BMC Medical Research Methodology 2017 17:44

    Published on: 17 March 2017

  8. Research article

    The feasibility of matching on a propensity score for acupuncture in a prospective cohort study of patients with chronic pain

    Propensity scores are typically applied in retrospective cohort studies. We describe the feasibility of matching on a propensity score derived from a retrospective cohort and subsequently applied in a prospect...

    Eric S. Johnson, John F. Dickerson, William M. Vollmer, Alee M. Rowley, Cheryl Ritenbaugh, Richard A. Deyo and Lynn DeBar

    BMC Medical Research Methodology 2017 17:42

    Published on: 16 March 2017

  9. Research article

    Assignment of adverse event indexing terms in randomized clinical trials involving spinal manipulative therapy: an audit of records in MEDLINE and EMBASE databases

    Reporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequa...

    Lindsay M. Gorrell, Roger M. Engel, Reidar P. Lystad and Benjamin T. Brown

    BMC Medical Research Methodology 2017 17:41

    Published on: 14 March 2017

  10. Research article

    Why sample selection matters in exploratory factor analysis: implications for the 12-item World Health Organization Disability Assessment Schedule 2.0

    Sample selection can substantially affect the solutions generated using exploratory factor analysis. Validation studies of the 12-item World Health Organization (WHO) Disability Assessment Schedule 2.0 (WHODAS...

    Cadeyrn J. Gaskin, Sylvie D. Lambert, Steven J. Bowe and Liliana Orellana

    BMC Medical Research Methodology 2017 17:40

    Published on: 11 March 2017

  11. Research article

    Trial Sequential Analysis in systematic reviews with meta-analysis

    Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded...

    Jørn Wetterslev, Janus Christian Jakobsen and Christian Gluud

    BMC Medical Research Methodology 2017 17:39

    Published on: 6 March 2017

  12. Research article

    AIMD - a validated, simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies

    Proliferation of terms describing the science of effectively promoting and supporting the use of research evidence in healthcare policy and practice has hampered understanding and development of the field. To ...

    Peter Bragge, Jeremy M. Grimshaw, Cynthia Lokker and Heather Colquhoun

    BMC Medical Research Methodology 2017 17:38

    Published on: 4 March 2017

  13. Research article

    A systematic review of studies with a representative sample of refugees and asylum seekers living in the community for participation in mental health research

    The aim was to review the literature to identify the most effective methods for creating a representative sample of refugee and asylum seeker groups living in the community to participate in health and mental ...

    Joanne C. Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas and Graham Meadows

    BMC Medical Research Methodology 2017 17:37

    Published on: 2 March 2017

  14. Research article

    Leveraging the EHR4CR platform to support patient inclusion in academic studies: challenges and lessons learned

    The development of Electronic Health Records (EHRs) in hospitals offers the ability to reuse data from patient care activities for clinical research. EHR4CR is a European public-private partnership aiming to d...

    Yannick Girardeau, Justin Doods, Eric Zapletal, Gilles Chatellier, Christel Daniel, Anita Burgun, Martin Dugas and Bastien Rance

    BMC Medical Research Methodology 2017 17:36

    Published on: 28 February 2017

  15. Research article

    Test-treatment RCTs are susceptible to bias: a review of the methodological quality of randomized trials that evaluate diagnostic tests

    There is a growing recognition for the need to expand our evidence base for the clinical effectiveness of diagnostic tests. Many international bodies are calling for diagnostic randomized controlled trials to ...

    Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Alice J. Sitch, Chris Hyde and Jonathan J. Deeks

    BMC Medical Research Methodology 2017 17:35

    Published on: 24 February 2017

  16. Research article

    Research waste in diagnostic trials: a methods review evaluating the reporting of test-treatment interventions

    The most rigorous method for evaluating the effectiveness of diagnostic tests is through randomised trials that compare test-treatment interventions: complex interventions comprising episodes of testing, decis...

    Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Sian Taylor-Phillips, Clare Davenport, Chris Hyde and Jonathan J. Deeks

    BMC Medical Research Methodology 2017 17:32

    Published on: 24 February 2017

  17. Research article

    Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice

    In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual ...

    Stephen D. Walter, Robin M. Turner, Petra Macaskill, Kirsten J. McCaffery and Les Irwig

    BMC Medical Research Methodology 2017 17:29

    Published on: 20 February 2017

  18. Research article

    Participant retention practices in longitudinal clinical research studies with high retention rates

    There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.

    Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham and Cheryl Dennison Himmelfarb

    BMC Medical Research Methodology 2017 17:30

    Published on: 20 February 2017

  19. Research Article

    On the censored cost-effectiveness analysis using copula information

    Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, ce...

    Charles Fontaine, Jean-Pierre Daurès and Paul Landais

    BMC Medical Research Methodology 2017 17:27

    Published on: 15 February 2017

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