Figure 2

Difference plots of estimates of pair-wise comparisons of the 12 antidepressant agents and placebo: regression model of published data vs. standard network meta-analysis (NMA) model of published data (left panel); selection models of published vs. standard NMA model of published data (right panel). The x-axes show the estimates from the standard NMA model applied to published data, the y-axes show the differences between the estimates from the adjustment (regression or selection) model of published data and the estimates from the standard NMA model of published data. Black dots are the 12 estimated drug effects relative to placebo; white dots are the 66 possible pair-wise comparisons between the 12 drugs.